EORTC QLQ-C30 assessment in Turkish patients with hematological malignancies

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dc.authorwosidTurgut, Burhan/A-2517-2016
dc.authorwosidHarmandar, Ferda/AAD-3862-2019
dc.contributor.authorPamuk, Guelsuem Emel
dc.contributor.authorHarmandar, Ferda
dc.contributor.authorErmantas, Nilay
dc.contributor.authorHarmandar, Orbay
dc.contributor.authorTurgut, Burhan
dc.contributor.authorDemir, Muzaffer
dc.contributor.authorVural, Oezden
dc.date.accessioned2024-06-12T11:03:05Z
dc.date.available2024-06-12T11:03:05Z
dc.date.issued2008
dc.departmentTrakya Üniversitesien_US
dc.description.abstractWe aimed to evaluate the prevalences of self-reported anxiety and depression symptoms in hematological malignancy patients and to determine the association between the presence of these disorders and the results of the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire-30 (EORTC QLQ-C30). One hundred and forty patients with a diagnosis of a hematological malignancy completed the Hospital Anxiety and Depression Scale (HADS) and the General Health Questionnaire. Patients with higher anxiety scores were more frequently inpatients, had higher EORTC general symptom scores, and they had lower cognitive, emotional, social functioning and global quality of life (QoL) scores (all p values < 0.05). Patients with higher depression scores had more frequently active disease and were inpatients; they had higher mean Eastern Cooperative Oncology Group performance scores, EORTC gastrointestinal system and general symptom scores, and significantly lower physical, role, emotional, social and cognitive functioning and global QoL scores (all p values < 0.01). During follow-up, it was observed that survival curves of patients with active disease who had higher HADS depression scores tended to be shorter than those with lower scores (p=0.1). Anxiety and depression are frequent in hematological malignancy patients and associated with poor QoL and performance status. In addition, the presence of self-reported depression might have a predictive value for poor prognosis.en_US
dc.identifier.doi10.1007/s00277-008-0445-4
dc.identifier.endpage310en_US
dc.identifier.issn0939-5555
dc.identifier.issn1432-0584
dc.identifier.issue4en_US
dc.identifier.pmid18219486en_US
dc.identifier.scopus2-s2.0-41249092073en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage305en_US
dc.identifier.urihttps://doi.org/10.1007/s00277-008-0445-4
dc.identifier.urihttps://hdl.handle.net/20.500.14551/21525
dc.identifier.volume87en_US
dc.identifier.wosWOS:000254176400008en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherSpringeren_US
dc.relation.ispartofAnnals Of Hematologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectHematological Malignancyen_US
dc.subjectAnxietyen_US
dc.subjectDepressionen_US
dc.subjectQuality Of Lifeen_US
dc.subjectEuropean Organization For Research And Treatment Of Cancer Quality Of Life Questionnaire-30 (EORTC QLQ-C30)en_US
dc.subjectQuality-Of-Lifeen_US
dc.subjectBone-Marrow-Transplantationen_US
dc.subjectCancer-Patientsen_US
dc.subjectImmune Functionen_US
dc.subjectDepressionen_US
dc.subjectLeukemiaen_US
dc.subjectChemotherapyen_US
dc.subjectReliabilityen_US
dc.subjectValidityen_US
dc.subjectAnxietyen_US
dc.titleEORTC QLQ-C30 assessment in Turkish patients with hematological malignanciesen_US
dc.typeArticleen_US

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