Urine analysis using FTIR spectroscopy: A study on healthy adults and children
Küçük Resim Yok
Tarih
2021
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Wiley-V C H Verlag Gmbh
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
Urine spectra from 108 healthy volunteers are studied by attenuated total refraction-Fourier transform infrared (ATR-FTIR) spectroscopy. The spectral features are correlated with observable urine components. The variation of spectra within a healthy population is quantified and a library of reference spectra is constructed. Using the band assignments, these spectra are compared with both age-wise and gender-wise. Children show the least intensity variations compared to both adult groups. Young adults show the highest variation, particularly in the 1650 to 1400 cm(-1) and 1200 to 900 cm(-1) regions. These results indicate the importance of the size of the control group in comparative studies utilizing FTIR. Age-wise comparisons reveal that phosphate and sulfate excretion decreases with age, and that the variance of phosphate among individuals is higher with adults. As for gender-wise comparisons, females show a slightly higher citrate content at 1390 cm(-1) regardless of the age and they show a higher variance in the 1200 to 1000 cm(-1) region when compared to men.
Açıklama
Anahtar Kelimeler
Adult Urine, Band Assignment, Children Urine, FTIR, Normal Variation, Urine Spectrum, Transform Infrared-Spectroscopy, Human Metabolome Database, Vibrational Spectroscopy, Citrate Excretion, Phosphorus, Serum, Hmdb, Creatinine, Phosphate, Diagnosis
Kaynak
Journal Of Biophotonics
WoS Q Değeri
Q2
Scopus Q Değeri
Q1
Cilt
14
Sayı
7
