Clinical importance of extended-spectrum ?-lactamase (PER-1-type)-producing Acinetobacter spp. and Pseudomonas aeruginosa strains

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dc.authoridKorten, VolkanO/0000-0002-9991-814X
dc.authoridVahaboglu, H/0000-0001-8217-1767
dc.authoridLeblebicioglu, Hakan/0000-0002-6033-8543
dc.authoridKocazeybek, Bekir S/0000-0003-1072-3846
dc.authorwosidKocazeybek, Bekir/D-8113-2018
dc.authorwosidKorten, VolkanO/HGT-7791-2022
dc.authorwosidKoksal, Iftihar/B-7518-2016
dc.authorwosidAkalin, Halis/AAU-8952-2020
dc.authorwosidVahaboglu, H/HHZ-1169-2022
dc.authorwosidLeblebicioglu, Hakan/A-3960-2016
dc.contributor.authorVahaboglu, H
dc.contributor.authorCoskunkan, F
dc.contributor.authorTansel, O
dc.contributor.authorOzturk, R
dc.contributor.authorSahin, N
dc.contributor.authorKoksal, I
dc.contributor.authorKocazeybek, B
dc.date.accessioned2024-06-12T11:19:31Z
dc.date.available2024-06-12T11:19:31Z
dc.date.issued2001
dc.departmentTrakya Üniversitesien_US
dc.description.abstractRecently, an extended-spectrum beta -lactamase (PER-I) was found to be disseminated among Acinetobacter spp, and Pseudomonas aeruginosa isolates in Turkey. A population-based cohort study was conducted to elucidate predictive mortality factors in patients with nosocomial infections caused by Acinetobacter spp. and P. aeruginosa, with particular reference to PER-1-type extended-spectrum beta -lactamase (ESBL) production. The study group comprised 16 and 21 non-survivors and 82 and 126 survivors in cohorts infected with Acinetobacter and E. aeruginosa, respectively. In the Acinetobacter-infected cohort, nosocomial pneumonia, hypotension and infection with a PER-positive isolate were independent predictors of mortality. In the P. aeruginosa-infected cohort, impaired consciousness, a PER-positive isolate, male sex and (with a negative relative risk) urinary tract infection were independent predictors of death. This study demonstrated the relationship of PER-1-type ESBL-producing Acinetobacter spp. and P. aeruginosa with poor clinical outcome.en_US
dc.identifier.endpage645en_US
dc.identifier.issn0022-2615
dc.identifier.issue7en_US
dc.identifier.pmid11444775en_US
dc.identifier.startpage642en_US
dc.identifier.urihttps://hdl.handle.net/20.500.14551/25235
dc.identifier.volume50en_US
dc.identifier.wosWOS:000169534300010en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherLippincott Williams & Wilkinsen_US
dc.relation.ispartofJournal Of Medical Microbiologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectOuter-Membraneen_US
dc.subjectResistanceen_US
dc.subjectBaumanniien_US
dc.subjectAcquisitionen_US
dc.subjectPneumoniaen_US
dc.subjectMortalityen_US
dc.subjectOutbreaken_US
dc.titleClinical importance of extended-spectrum ?-lactamase (PER-1-type)-producing Acinetobacter spp. and Pseudomonas aeruginosa strainsen_US
dc.typeArticleen_US

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