Synthesis and Characterization of New Binaphthyl-Linked Phenanthroline-, Bipyridine-, or Pyridine-Derived Ligands, and the Study of Their Cytotoxic Activity

Basit Öğe Kaydı
dc.authoridUluçam, Gühergül/0000-0001-6481-8483
dc.authoridBenkli, Kadriye/0000-0002-9042-8718
dc.authorwosidUluçam, Gühergül/AAH-2862-2019
dc.contributor.authorBeynek, Nesrin
dc.contributor.authorUlucam, Gueherguel
dc.contributor.authorBenkli, Kadriye
dc.contributor.authorKoparal, Ayse Tansu
dc.date.accessioned2024-06-12T11:17:53Z
dc.date.available2024-06-12T11:17:53Z
dc.date.issued2008
dc.departmentTrakya Üniversitesien_US
dc.description.abstractIn the present work, we describe the synthesis and characterization of five new versatile acyclic or macrocyclic ligands containing binaphtyl-linked pyridine, bipyridine, or phenanthroline groups in their framework (see Schemes 1-4). The structures of the ligands were elucidated on the basis of elemental analyses. 1R, (1)H-NMR, (13)C-NMR, and FAB mass spectra. The cytotoxicity of these compounds was tested in vitro by using the tetrazolium salt reduction (MTT) assay on A549 (human lung carcinoma epithelial like) cells. All Of the tested compounds induced time- and concentration-dependent cytotoxic effect.en_US
dc.identifier.doi10.1002/hlca.200890223
dc.identifier.endpage2096en_US
dc.identifier.issn0018-019X
dc.identifier.issue11en_US
dc.identifier.scopus2-s2.0-57149088513en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage2089en_US
dc.identifier.urihttps://doi.org/10.1002/hlca.200890223
dc.identifier.urihttps://hdl.handle.net/20.500.14551/24884
dc.identifier.volume91en_US
dc.identifier.wosWOS:000261485200008en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherWiley-V C H Verlag Gmbhen_US
dc.relation.ispartofHelvetica Chimica Actaen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectComplexen_US
dc.subjectBinolen_US
dc.subjectCoordinationen_US
dc.subjectCadmium(Ii)en_US
dc.subjectChemistryen_US
dc.subjectDnaen_US
dc.titleSynthesis and Characterization of New Binaphthyl-Linked Phenanthroline-, Bipyridine-, or Pyridine-Derived Ligands, and the Study of Their Cytotoxic Activityen_US
dc.typeArticleen_US

Dosyalar

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu