The frequency of thyroid antibodies in fibromyalgia patients and their relationship with symptoms

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dc.authorwosidCakir, Necati/AAG-7283-2019
dc.contributor.authorPamuk, Omer Nuri
dc.contributor.authorCakir, Necati
dc.date.accessioned2024-06-12T10:59:21Z
dc.date.available2024-06-12T10:59:21Z
dc.date.issued2007
dc.departmentTrakya Üniversitesien_US
dc.description.abstractWe determined the frequency of thyroid autoantibodies in fibromyalgia (FM) patients and the relationship between FM symptoms and these antibodies. Euthyroid 128 FM patients, 64 rheumatoid arthritis (RA) patients, and 64 healthy control subjects were included in the study. The sociodemographic features and the clinical features of FM patients were determined. By using a visual analog scale, patients were questioned about the severity of FM-related symptoms. All patients were administered with Duke-Anxiety Depression (Duke-AD) scale, the physical function items of the fibromyalgia impact questionnaire scale. Thyroid autoimmunity was defined as the presence of detectable antithyroglobulin (TgAb) and/or antithyroid peroxidase (TPOAb) antibodies by the immunometric methods. Patients with a connective tissue disorder, hypo- or hyperthyroidism, and patients who had psychiatric treatment within the last 6 months were not included into the study. The frequencies of thyroid autoimmunity in FM (34.4%) and RA (29.7%) patients were significantly higher than controls (18.8%) (p < 0.05). Twenty-six (20.3%) FM patients had positive TgAb and 31 (24.2%) had positive TPOAb. When patients with thyroid autoimmunity were compared to others, it was seen that the mean age, the percentage of postmenopausal patients, the frequency of dryness of the mouth, and the percentage of patients with a previous psychiatric treatment were higher in this group (p < 0.05). FM patients had thyroid autoimmunity similar to the frequency in RA and higher than controls. Age and postmenopausal status seemed to be associated with thyroid autoimmunity in FM patients. The presence of thyroid autoimmunity had no relationship with the depression scores of FM patients.en_US
dc.identifier.doi10.1007/s10067-006-0237-y
dc.identifier.endpage59en_US
dc.identifier.issn0770-3198
dc.identifier.issn1434-9949
dc.identifier.issue1en_US
dc.identifier.pmid16541203en_US
dc.identifier.scopus2-s2.0-33845866350en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage55en_US
dc.identifier.urihttps://doi.org/10.1007/s10067-006-0237-y
dc.identifier.urihttps://hdl.handle.net/20.500.14551/20402
dc.identifier.volume26en_US
dc.identifier.wosWOS:000243032100011en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherSpringer London Ltden_US
dc.relation.ispartofClinical Rheumatologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectDepressionen_US
dc.subjectFibromyalgiaen_US
dc.subjectThyroid Autoimmunityen_US
dc.subjectThyroid Peroxidase Antibodyen_US
dc.subjectAutoimmune-Thyroiditisen_US
dc.subjectImpact Questionnaireen_US
dc.subjectDepressionen_US
dc.subjectManifestationsen_US
dc.subjectAssociationen_US
dc.subjectDysfunctionen_US
dc.titleThe frequency of thyroid antibodies in fibromyalgia patients and their relationship with symptomsen_US
dc.typeArticleen_US

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