ETİLENDİAMİN DİHİDROKLORİD’İN (EDA-2HCl) SIÇANLARDA KARACİĞER VE BÖBREK DOKULARI ÜZERİNE ETKİLERİNİN ARAŞTIRILMASI

dc.contributor.authorAda, Zeynep Dilek
dc.contributor.authorÇerkezkayabekir, Ayşegül
dc.date.accessioned2021-11-20T10:27:23Z
dc.date.available2021-11-20T10:27:23Z
dc.date.issued2009
dc.departmentFakülteler, Fen Fakültesi, Biyoloji Bölümüen_US
dc.description.abstractEthylenediamine dihydrochloride (EDA-2HCl, 50 mg/kg/day) was given by intramuscular (i.m.) injection to Wistar albino rats for ten days and change in body weight, the histopathologically effects on liver and kidney were examined. Thus, gains in body weight was not changed significantly (p lt;0,05). It was observed that endothelial degeneration of vein, mononuclear cell infiltration, degeneration of hepatocyte membrane, hypertrophy, loosing of cytoplasm and nucleus, vacuolization in cytoplasm, picnotic nucleus in hepatocytes and loss of integrity in the tissue were observed in liver. Increasing of distance between parietal and visceral layer of Bowman capsule, atrophy in Glomerulus, loosing of Glomerulus, degeneration of membrane in epithelia of tubules, loosing of nucleus and cytoplasm in epithelial cell, hypertrophy, vacuolization in cytoplasm, picnotic nucleus, degenerative nucleus and cytoplasmic residues in tubule lumen were observed in kidney. Besides, thickening of basal membrane of hepatocytes in liver and epithelia of tubules in kidney were determined.en_US
dc.description.abstractEtilendiamin dihidroklorid (EDA-2HCl, 50 mg/kg/gün) on gün boyunca Wistar albino sıçanlara intramuskular (i.m.) enjeksiyon yoluyla verildi ve vücut ağırlıklarındaki değişim, karaciğer ve böbrek dokularındaki histopatolojik değişiklikler incelendi. Buna göre; vücut ağırlığında anlamlı bir değişim gözlenmedi (pen_US
dc.identifier.dergipark246027en_US
dc.identifier.endpage196en_US
dc.identifier.issn1305-6468
dc.identifier.issue2en_US
dc.identifier.startpage189en_US
dc.identifier.urihttps://dergipark.org.tr/tr/pub/trakyafbd/issue/23003/246027
dc.identifier.urihttps://dergipark.org.tr/tr/download/article-file/213865
dc.identifier.urihttps://hdl.handle.net/20.500.14551/6346
dc.identifier.volume10en_US
dc.language.isotren_US
dc.publisherTrakya Üniversitesien_US
dc.relation.ispartofTrakya Üniversitesi Fen Bilimleri Dergisien_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectEthylenediamine dihydrochlorideen_US
dc.subjecthistopathologyen_US
dc.subjectkidneyen_US
dc.subjectliveren_US
dc.subjectBöbreken_US
dc.subjectetilendiamin dihidrokloriden_US
dc.subjecthistopatolojien_US
dc.subjectkaraciğeren_US
dc.titleETİLENDİAMİN DİHİDROKLORİD’İN (EDA-2HCl) SIÇANLARDA KARACİĞER VE BÖBREK DOKULARI ÜZERİNE ETKİLERİNİN ARAŞTIRILMASIen_US
dc.title.alternativeThe Investigation of Effects of Ethylenediamine Dihydrochloride (Eda-2Hcl) on Liver and Kidney in Ratsen_US
dc.typeArticleen_US

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