The effect of thyroid functions on contrast-induced nephropathy in patients undergoing coronary angiography and percutaneous coronary intervention

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dc.authorwosidArı, Hasan/AAL-1814-2020
dc.contributor.authorGurdogan, Muhammet
dc.contributor.authorAri, Hasan
dc.date.accessioned2024-06-12T10:58:26Z
dc.date.available2024-06-12T10:58:26Z
dc.date.issued2019
dc.departmentTrakya Üniversitesien_US
dc.description.abstractObjective: To investigate the effects of thyroidism on the development of contrast-induced nephropathy in patients undergoing coronary angiography and percutaneous coronary intervention. Methods: The prospective, observational study was conducted at Trakya University Faculty of Medicine, Edirne, Turkey, from October 1, 2016, to October 1, 2017, and comprised patients with hypothyroidism, hyperthyroidism and euthyroid patients. Thyroid and renal functions were evaluated from blood samples taken before the procedure. The definition of contrast-induced nephropathy included absolute (0.5 mg/dL) or relative increase (25%) in serum creatinine 48-72 h after exposure to a contrast agent compared with baseline serum creatinine values. SPSS 10 was used for data analysis. Results: Of the 162 patients, 58(35.8%) had hypothyroidism, 47(29%) hyperthyroidism and 57(35.2%) euthyroid. Contrast-induced nephropathy was significantly higher in hypothyroid and hyperthyroid subjects compared to euthyroid group (p<0.001 each). Univariate analysis showed contrast volume, procedure, albumin value, hypothyroidism and hyperthyroidism to be independent predictors of contrast-induced nephropathy (p<0.05 each), but multivariate analysis only showed hypothyroidism and the hyperthyroidism as the independent predictors (p<0.01 each). Conclusion: Contrast-induced nephropathy rate was increased in patients with malfunctioning thyroid, Hypothyroidism and hyperthyroidism were found to be independent predictors of contrast-induced nephropathy.en_US
dc.identifier.doi10.5455/JPMA.298993
dc.identifier.endpage1458en_US
dc.identifier.issn0030-9982
dc.identifier.issue10en_US
dc.identifier.pmid31622296en_US
dc.identifier.scopus2-s2.0-85073517814en_US
dc.identifier.scopusqualityQ4en_US
dc.identifier.startpage1453en_US
dc.identifier.urihttps://doi.org/10.5455/JPMA.298993
dc.identifier.urihttps://hdl.handle.net/20.500.14551/20067
dc.identifier.volume69en_US
dc.identifier.wosWOS:000490552000007en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherPakistan Medical Assocen_US
dc.relation.ispartofJournal Of The Pakistan Medical Associationen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectContrast-Induced Nephropathyen_US
dc.subjectCoronary Angiographyen_US
dc.subjectPercutaneous Coronary Interventionen_US
dc.subjectThyroid Functionsen_US
dc.subjectAcute-Renal-Failureen_US
dc.subjectRisk-Factorsen_US
dc.subjectDysfunctionen_US
dc.subjectCinen_US
dc.titleThe effect of thyroid functions on contrast-induced nephropathy in patients undergoing coronary angiography and percutaneous coronary interventionen_US
dc.typeArticleen_US

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