Acute effect of DDD versus VVI pacing on arterial distensibility

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dc.authoridAltun, Armagan/0000-0002-3233-8263
dc.authorwosidYildiz, Mustafa/D-6892-2019
dc.authorwosidAltun, Armagan/ABB-5844-2020
dc.contributor.authorAltun, A
dc.contributor.authorErdogan, O
dc.contributor.authorYildiz, M
dc.date.accessioned2024-06-12T10:52:46Z
dc.date.available2024-06-12T10:52:46Z
dc.date.issued2004
dc.departmentTrakya Üniversitesien_US
dc.description.abstractPulse wave velocity (PWV) is a new technique and frequently used today to determine the elastic distensibility of great arteries. Increased arterial stiffness and PWV have been proposed as possible mechanisms in the initiation and/or progression and/or complications of atherosclerosis and cardiovascular disease. We evaluated the acute effect of two frequently used pacing modes (DDD vs. VVI) on arterial distensibility using PWV. Methods: Seventeen patients ( age, 56 +/- 14 years) implanted with DDD pacemakers were included in the study. All patients were pacemaker dependent and continuously paced at the programmed rate. PWV was measured first in DDD mode, and then the mode was switched to VVI, and PWV was measured again at the same programmed heart rate as in the DDD mode. Results: Although systolic blood pressure significantly decreased from 129 +/- 18 to 119 +/- 16 mm Hg (p = 0.001) after switching the mode from DDD to VVI, diastolic blood pressure (81 +/- 12 vs. 80 +/- 13 mm Hg; p = 0.38) did not change. In addition, PWV significantly increased from 11 +/- 2.46 m/s in DDD mode to 11.29 +/- 2.43 m/s (p = 0.01) after having been programmed to VVI mode. Conclusions: Our results suggest that VVI pacing increases PWV, and therefore decreases arterial distensibility, and thus may contribute to the development and progression of atherosclerosis. Copyright (C) 2004 S. Karger AG, Basel.en_US
dc.identifier.doi10.1159/000077910
dc.identifier.endpage92en_US
dc.identifier.issn0008-6312
dc.identifier.issue2en_US
dc.identifier.pmid15103178en_US
dc.identifier.scopus2-s2.0-4043063755en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage89en_US
dc.identifier.urihttps://doi.org/10.1159/000077910
dc.identifier.urihttps://hdl.handle.net/20.500.14551/18826
dc.identifier.volume102en_US
dc.identifier.wosWOS:000224208300005en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherKargeren_US
dc.relation.ispartofCardiologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectAtherosclerosisen_US
dc.subjectDistensibilityen_US
dc.subjectPacemakeren_US
dc.subjectPulse Wave Velocityen_US
dc.subjectStiffnessen_US
dc.subjectSympathetic-Nerve Activityen_US
dc.subjectStiffnessen_US
dc.titleAcute effect of DDD versus VVI pacing on arterial distensibilityen_US
dc.typeArticleen_US

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