Local oxidative stress in interdigital tinea pedis

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dc.authoridKurutas, Ergul Belge/0000-0002-6653-4801;
dc.authorwosidKurutas, Ergul Belge/CAJ-2682-2022
dc.authorwosidGUNGOR, MELTEM/ABE-2403-2020
dc.contributor.authorOzturk, Perihan
dc.contributor.authorArican, Ozer
dc.contributor.authorKurutas, Ergul B.
dc.contributor.authorKarakas, Tugba
dc.contributor.authorGungor, Meltem
dc.date.accessioned2024-06-12T10:55:57Z
dc.date.available2024-06-12T10:55:57Z
dc.date.issued2013
dc.departmentTrakya Üniversitesien_US
dc.description.abstractSeveral skin diseases are believed to be associated with oxidative stress. Tinea pedis is an infection of the feet caused by fungi. The infectious diseases caused by dermatophytes are mainly related to the enzymes produced by these fungi. The cutaneous oxidative stress status of tinea pedis has not been demonstrated in the published work up to now. The aim of the present study was to evaluate the role of oxidative stress in affected skin areas in a group of patients with interdigital tinea pedis. Thirty-one consecutive patients with a diagnosis of unilateral interdigital tinea pedis were enrolled. The samples were obtained by scraping the skin surface. Oxidative stress biomarkers such as superoxide dismutase, catalase and malondialdehyde levels were measured spectrophotometrically. The activities of superoxide dismutase and catalase and the levels of malondialdehyde were significantly higher on the lesional area than the non-lesional area (P<0.001). According to sex and fungal subtypes, there was no significant difference in the levels of oxidative stress biomarkers in patients with tinea pedis (0.05). Our results suggested that antioxidant defense of lesional skin surface was higher compared to non-lesional skin. This is possibly due to a compensatory response to various fungal infections and thereby protects the cells against oxidative damage.en_US
dc.identifier.doi10.1111/1346-8138.12043
dc.identifier.endpage117en_US
dc.identifier.issn0385-2407
dc.identifier.issn1346-8138
dc.identifier.issue2en_US
dc.identifier.pmid23216444en_US
dc.identifier.scopus2-s2.0-84874113329en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage114en_US
dc.identifier.urihttps://doi.org/10.1111/1346-8138.12043
dc.identifier.urihttps://hdl.handle.net/20.500.14551/19595
dc.identifier.volume40en_US
dc.identifier.wosWOS:000315028800007en_US
dc.identifier.wosqualityQ1en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherWileyen_US
dc.relation.ispartofJournal Of Dermatologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectCatalaseen_US
dc.subjectMalondialdehydeen_US
dc.subjectSuperoxide Dismutaseen_US
dc.subjectTinea Pedisen_US
dc.titleLocal oxidative stress in interdigital tinea pedisen_US
dc.typeArticleen_US

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