CLINICALLY UNDETECTABLE OCCULT THYROID PAPILLARY CARCINOMA PRESENTING WITH CERVICAL LYMPH NODE METASTASIS

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dc.authoridAytürk Salt, Semra/0000-0002-1560-3459
dc.authoridCelik, Mehmet/0000-0001-7364-370X
dc.authorwosidAytürk Salt, Semra/U-4265-2017
dc.authorwosidCan, Nuray/D-3452-2016
dc.authorwosidCelik, Mehmet/AAA-8773-2021
dc.contributor.authorTastekin, E.
dc.contributor.authorCan, N.
dc.contributor.authorAyturk, S.
dc.contributor.authorCelik, M.
dc.contributor.authorUstun, F.
dc.contributor.authorGuldiken, S.
dc.contributor.authorSezer, A.
dc.date.accessioned2024-06-12T11:16:26Z
dc.date.available2024-06-12T11:16:26Z
dc.date.issued2016
dc.departmentTrakya Üniversitesien_US
dc.description.abstractBackground. Occult papillary thyroid carcinoma presented as isolated cervical lymphadenopathy without clinical and radiologic findings has been rarely reported. Case report. A 47 years old female patient admitted to otorhinolaryngology clinic with 4X3 cm sized cervical mass. Physical examination of the patient was noted as a nontender, firm, mobile lymph node at right lateral cervical region. There was no inflammatory or infection disease in the history of patients anamnesis and no abnormal value on laboratory tests. Ultrasound screening of the neck detected a lymph node with suspicious features for malignancy. Head and neck examination was normal and there is no evidence of a tumoral mass or nodule in the thyroid gland. Whole body scan of MRI showed no pathologic sign both in the neck and body. Excisional biopsy was performed and revealed a carcinoma with papillary morphology. Immunohistochemical staining features of the tumor confirmed a papillary carcinoma derived from the thyroid gland. Second look USG of the neck and thyroid was performed but it revealed no tumoral mass. The patient underwent total thyroidectomy with right functional and central lymph node dissection. Histological examination of the thyroid gland showed multicentric 2 mm sized, three foci of papillary carcinoma located in bilateral thyroid lobes and metastatic lymph nodes in the right side of the neck. Conclusion. A metastatic cervical lymph node can be evidence of a clinically undetected occult papillary thyroid carcinoma. Specific immunohistochemistry staining of specimen may lead to appropriate surgery and progression of carcinoma may be hindered by application of additional RAI therapy.en_US
dc.identifier.doi10.4183/aeb.2016.72
dc.identifier.endpage76en_US
dc.identifier.issn1841-0987
dc.identifier.issn1843-066X
dc.identifier.issue1en_US
dc.identifier.pmid31258804en_US
dc.identifier.scopus2-s2.0-85011968867en_US
dc.identifier.scopusqualityQ4en_US
dc.identifier.startpage72en_US
dc.identifier.urihttps://doi.org/10.4183/aeb.2016.72
dc.identifier.urihttps://hdl.handle.net/20.500.14551/24301
dc.identifier.volume12en_US
dc.identifier.wosWOS:000372668300013en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherEditura Acad Romaneen_US
dc.relation.ispartofActa Endocrinologica-Bucharesten_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectThyroiden_US
dc.subjectPapillary Carcinomaen_US
dc.subjectPapillary Micro-Carcinomaen_US
dc.subjectOccult Carcinomaen_US
dc.subjectLateral Neck Massen_US
dc.subjectCanceren_US
dc.titleCLINICALLY UNDETECTABLE OCCULT THYROID PAPILLARY CARCINOMA PRESENTING WITH CERVICAL LYMPH NODE METASTASISen_US
dc.typeArticleen_US

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