Prognostic Role of Tumor Percentage in Multiparametric MRI for Upgrade Prediction Before Radical Prostatectomy

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dc.authoridecer, gökhan/0000-0002-2805-8664
dc.authoridşahin, Mehmet Fatih/0000-0002-0926-3005
dc.authoridYazici, Cenk Murat/0000-0001-6140-5181
dc.authorwosidecer, gökhan/HJH-7002-2023
dc.authorwosidşahin, Mehmet Fatih/HDL-9427-2022
dc.authorwosidYazici, Cenk Murat/AAA-4330-2020
dc.contributor.authorArikan, Mehmet Guerkan
dc.contributor.authorEcer, Goekhan
dc.contributor.authorSahin, Mehmet Fatih
dc.contributor.authorHereklioglu, Savas
dc.contributor.authorGoekalp, Fatih
dc.contributor.authorArda, Ersan
dc.contributor.authorAkguel, Burak
dc.date.accessioned2024-06-12T11:08:46Z
dc.date.available2024-06-12T11:08:46Z
dc.date.issued2024
dc.departmentTrakya Üniversitesien_US
dc.description.abstractObjective: To determine the parameters that can predict upgrade with multiparametric magnetic resonance imaging (mpMRI) findings before radical prostatectomy Materials and Methods: The study included 69 patients who were diagnosed with prostate cancer (PCa) between January 2017-December 2020 and subsequently underwent RP. Patients were divided into two groups by comparing prostate biopsies and RP specimens as patients with upgrade (group 1) and patients without upgrade (group 2). Of the 69 patients, 26 were in group 1 and 43 in group 2. The images were evaluated by a single radiologist experienced in mpMRI using the Prostate Imaging Reporting and Data System v2.1 scoring system. Biopsy and RP pathology specimens were evaluated by an experienced neuropathologist. Results: The median prostate-specific antigen (PSA) levels were higher in patients with upgraded pathology [8.60 (5.90-14.00) ng/dL vs. 7.70 (5.20-10.00) ng/dL, respectively; p=0.040]. The prostate volume [31.88 (23.40-51.48) vs. 48.06 (23.40-87.35); p=0.009] and PSA density [3.72 (2.17-5.62) vs. 5.75 (3.35-9.6), respectively; p=0.007] were lower in patients with upgraded pathology. The tumor percentage on mpMRI was not different between the groups [3.70 (1.80-16.20 Conclusions: Although the percentage of tumors on multiparametric mpMRI is an inadequate pattern to predict upgrade in PCa patients, prospective studiesen_US
dc.identifier.doi10.4274/uob.galenos.2024.2023.7.1
dc.identifier.endpage41en_US
dc.identifier.issn2147-2270
dc.identifier.issue1en_US
dc.identifier.startpage36en_US
dc.identifier.urihttps://doi.org/10.4274/uob.galenos.2024.2023.7.1
dc.identifier.urihttps://hdl.handle.net/20.500.14551/22566
dc.identifier.volume23en_US
dc.identifier.wosWOS:001198126600003en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.language.isoenen_US
dc.publisherGalenos Publ Houseen_US
dc.relation.ispartofUroonkoloji Bulteni-Bulletin Of Urooncologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectMultiparametric Magnetic Resonance Imagingen_US
dc.subjectProstate Canceren_US
dc.subjectRadical Prostatectomyen_US
dc.subjectTumor Percentageen_US
dc.subjectUpgradeen_US
dc.subjectExtracapsular Extensionen_US
dc.subjectGleason Scoresen_US
dc.subjectCanceren_US
dc.subjectBiopsyen_US
dc.subjectVolumeen_US
dc.subjectRisken_US
dc.subjectAssociationen_US
dc.subjectInvolvementen_US
dc.subjectConcordanceen_US
dc.titlePrognostic Role of Tumor Percentage in Multiparametric MRI for Upgrade Prediction Before Radical Prostatectomyen_US
dc.typeArticleen_US

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