Reproducibility of Automatic Endothelial Cell Analysis Performed With Non-Contact Specular Microscopy

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dc.contributor.authorGurlu, Vuslat Pelitli
dc.contributor.authorBulbul, Ebru Demet
dc.contributor.authorErda, Sait
dc.date.accessioned2024-06-12T11:15:28Z
dc.date.available2024-06-12T11:15:28Z
dc.date.issued2006
dc.departmentTrakya Üniversitesien_US
dc.description.abstractObjective: To investigate the reproducibility of automatic endothelial cell analysis performed with non-contact specular microscopes. Method: Fifteen eyes of 15 case were included in the study. From each eye 2 consecutive endothelial images of central cornea obtained with the Topcon SP-2000P by the first observer. Firstly, first image of each eye was assessed by correcting the cell borders defined by automatic analysis system (IMAGEnet) and using standart frame. Intra-operator reproducibility was investigated by comparison of results of these analysis with the analysis results of uncorrected cell borders defined by the automatic analysis system (I), with the use of smaller frame rather than the standard frame (II) and with the analysis results of second image of each eye captured by the first observer (III). In the second phase, inter-operator reproducibility was investigated by comparison of the results of the first observer with the results obtained by assessment of the first image of each eye by a second observer. Findings: Both the assesment made for the intra-operator reproducibility and inter-operator reproducibility revealed a medium-low degree of correlation for the coefficient of variation and hexagonality rates while a high correlation was observed for the values of cell density and average cell area. Conclusion: In conclusion, assesments made with the non-contact specular microscopy and automatic analysis system have a substantially high rate of reproducibility when standard frame and corrected cell borders are used.en_US
dc.identifier.endpage305en_US
dc.identifier.issn1300-0659
dc.identifier.issn2147-2661
dc.identifier.issue4en_US
dc.identifier.startpage300en_US
dc.identifier.urihttps://hdl.handle.net/20.500.14551/23950
dc.identifier.volume36en_US
dc.identifier.wosWOS:000217216800002en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.language.isotren_US
dc.publisherTurkish Ophthalmological Socen_US
dc.relation.ispartofTurk Oftalmoloji Dergisi-Turkish Journal Of Ophthalmologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectSpecular Microscopyen_US
dc.subjectCorneal Endotheliumen_US
dc.subjectCell Densityen_US
dc.subjectCoefficient Of Variationen_US
dc.subjectHexagonalityen_US
dc.titleReproducibility of Automatic Endothelial Cell Analysis Performed With Non-Contact Specular Microscopyen_US
dc.typeArticleen_US

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