Increased Severe Cases and New-Onset Type 1 Diabetes Among Children Presenting With Diabetic Ketoacidosis During First Year of COVID-19 Pandemic in Turkey

Basit Öğe Kaydı
dc.authoridKaraoglan, Murat/0000-0002-2861-3568
dc.authoridAkçay, Nihal/0000-0002-8273-2226
dc.authoridYILMAZ, Resul/0000-0001-7672-8100
dc.authoridSOYDAN, EKIN/0000-0003-2626-5499
dc.authoridUysal Yazici, Mutlu/0000-0001-7377-4718
dc.authoridOZTURK, ZEYNELABIDIN/0000-0001-8548-4144
dc.authoriddursun, oguz/0000-0001-5482-3780
dc.authorwosidKaraoglan, Murat/V-5588-2018
dc.authorwosidAkçay, Nihal/ACQ-1470-2022
dc.authorwosidYILMAZ, Resul/A-2825-2012
dc.authorwosidSOYDAN, EKIN/JDW-3813-2023
dc.authorwosidUysal Yazici, Mutlu/ACA-8750-2022
dc.authorwosidOZTURK, ZEYNELABIDIN/I-9370-2013
dc.authorwosiddursun, oguz/C-1604-2016
dc.contributor.authorKiral, Eylem
dc.contributor.authorKirel, Birgul
dc.contributor.authorHavan, Merve
dc.contributor.authorKeskin, Mehmet
dc.contributor.authorKaraoglan, Murat
dc.contributor.authorYildirim, Ahmet
dc.contributor.authorKangin, Murat
dc.date.accessioned2024-06-12T10:58:42Z
dc.date.available2024-06-12T10:58:42Z
dc.date.issued2022
dc.departmentTrakya Üniversitesien_US
dc.description.abstractIntroductionThere have been some significant changes regarding healthcare utilization during the COVID-19 pandemic. Majority of the reports about the impact of the COVID-19 pandemic on diabetes care are from the first wave of the pandemic. We aim to evaluate the potential effects of the COVID-19 pandemic on the severity of diabetic ketoacidosis (DKA) and new onset Type 1 diabetes presenting with DKA, and also evaluate children with DKA and acute COVID-19 infection. MethodsThis is a retrospective multi-center study among 997 children and adolescents with type 1 diabetes who were admitted with DKA to 27 pediatric intensive care units in Turkey between the first year of pandemic and pre-pandemic year. ResultsThe percentage of children with new-onset Type 1 diabetes presenting with DKA was higher during the COVID-19 pandemic (p < 0.0001). The incidence of severe DKA was also higher during the COVID-19 pandemic (p < 0.0001) and also higher among children with new onset Type 1 diabetes (p < 0.0001). HbA1c levels, duration of insulin infusion, and length of PICU stay were significantly higher/longer during the pandemic period. Eleven patients tested positive for SARS-CoV-2, eight were positive for new onset Type 1 diabetes, and nine tested positive for severe DKA at admission. DiscussionThe frequency of new onset of Type 1 diabetes and severe cases among children with DKA during the first year of the COVID-19 pandemic. Furthermore, the cause of the increased severe presentation might be related to restrictions related to the pandemic; however, need to evaluate the potential effects of SARS-CoV-2 on the increased percentage of new onset Type 1 diabetes.en_US
dc.identifier.doi10.3389/fped.2022.926013
dc.identifier.issn2296-2360
dc.identifier.pmid35844756en_US
dc.identifier.scopus2-s2.0-85134183367en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.urihttps://doi.org/10.3389/fped.2022.926013
dc.identifier.urihttps://hdl.handle.net/20.500.14551/20168
dc.identifier.volume10en_US
dc.identifier.wosWOS:000826479900001en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherFrontiers Media Saen_US
dc.relation.ispartofFrontiers In Pediatricsen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectCOVID-19en_US
dc.subjectChildrenen_US
dc.subjectDiabetesen_US
dc.subjectDiabetic Ketoacidosisen_US
dc.subjectPandemicen_US
dc.subjectPediatric Intensive Care Uniten_US
dc.subjectRisken_US
dc.titleIncreased Severe Cases and New-Onset Type 1 Diabetes Among Children Presenting With Diabetic Ketoacidosis During First Year of COVID-19 Pandemic in Turkeyen_US
dc.typeArticleen_US

Dosyalar

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
PubMed İndeksli Yayınlar Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu