Systemic Immune-Inflammation Index: A Novel Predictor of Coronary Thrombus Burden in Patients with Non-ST Acute Coronary Syndrome

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dc.authoridÖzkan, Uğur/0000-0002-7552-7654
dc.authoridYılmaz, Efe/0000-0003-2976-3063
dc.authoridAkkuş, Ömer Ferudun/0000-0001-5938-2371
dc.authoridÖztürk, Cihan/0000-0001-8694-1693
dc.authoriddemir, melik/0000-0003-1711-6707
dc.authoridAltay, Servet/0000-0001-7112-3970
dc.authoridGURDOGAN, Muhammet/0000-0001-5650-9066
dc.authorwosidÖzkan, Uğur/ACR-6091-2022
dc.authorwosidYılmaz, Efe/HOF-2605-2023
dc.authorwosidDemir, Melik/HGE-0608-2022
dc.authorwosidAkkuş, Ömer Ferudun/HGE-0531-2022
dc.authorwosidÖztürk, Cihan/HJI-3312-2023
dc.authorwosidAltay, Servet/C-1387-2018
dc.contributor.authorOzkan, Ugur
dc.contributor.authorGuerdogan, Muhammet
dc.contributor.authoroeztuerk, Cihan
dc.contributor.authorDemir, Melik
dc.contributor.authorAkkus, Oemer Feridun
dc.contributor.authorYilmaz, Efe
dc.contributor.authorAltay, Servet
dc.date.accessioned2024-06-12T11:15:56Z
dc.date.available2024-06-12T11:15:56Z
dc.date.issued2022
dc.departmentTrakya Üniversitesien_US
dc.description.abstractBackground and Objectives: Excessive coronary thrombus burden is known to cause an increase in mortality and major adverse cardiac events (MACEs) in NSTE-ACS (non-ST acute coronary syndrome) patients. We investigated the association between the systemic immune-inflammation index (SII) and coronary thrombus burden in patients with non-ST segment elevation myocardial infarction (NSTEMI) who underwent coronary angiography and percutaneous coronary intervention (PCI). Materials and Methods: A total of 389 patients with the diagnosis of NSTEMI participated in our study. Coronary thrombus burden was classified in the TIMI (thrombolysis in myocardial infarction) thrombus grade scale and patients were divided into two groups: a TIMI thrombus grade 0-1 group (n = 209, 157 males) and a TIMI thrombus grade 2-6 group (n = 180, 118 males). Demographics, angiographic lesion images, coronary thrombus burden, clinical risk factors, laboratory parameters, and SII score were compared between the two groups. Results: The high thrombus burden patient group had a higher neutrophil count, WBC count, platelet count, and systemic immune-inflammation index (SII) (p < 0.001). The receiver operating characteristic (ROC) curve analysis showed that at a cutoff of 1103, the value of SII manifested 74.4% sensitivity and 74.6% specificity for detecting a high coronary thrombus burden. Conclusions: Our study showed that the SII levels at hospital admission were independently associated with high coronary thrombus with NSTEMI.en_US
dc.identifier.doi10.3390/medicina58020143
dc.identifier.issn1010-660X
dc.identifier.issn1648-9144
dc.identifier.issue2en_US
dc.identifier.pmid35208466en_US
dc.identifier.scopus2-s2.0-85123384958en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.urihttps://doi.org/10.3390/medicina58020143
dc.identifier.urihttps://hdl.handle.net/20.500.14551/24130
dc.identifier.volume58en_US
dc.identifier.wosWOS:000769024500001en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherMdpien_US
dc.relation.ispartofMedicina-Lithuaniaen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectSystemic Immune-Inflammation Indexen_US
dc.subjectCoronary Thrombus Burdenen_US
dc.subjectNon-St Acute Coronary Syn-Dromeen_US
dc.subjectAtherosclerosisen_US
dc.subjectPlaque Ruptureen_US
dc.subjectThrombus Formationen_US
dc.subjectPretreatmenten_US
dc.subjectAcute Myocardial-Infarctionen_US
dc.subjectOutcomesen_US
dc.subjectClopidogrelen_US
dc.subjectLymphocyteen_US
dc.subjectNeutrophilen_US
dc.subjectMortalityen_US
dc.subjectRatioen_US
dc.subjectRisken_US
dc.titleSystemic Immune-Inflammation Index: A Novel Predictor of Coronary Thrombus Burden in Patients with Non-ST Acute Coronary Syndromeen_US
dc.typeArticleen_US

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