Assessing PET Parameters in Oncologic 18F-FDG Studies

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dc.authoridSarikaya, Ismet/0000-0002-1087-580X
dc.authorwosidSarikaya, Ismet/G-7881-2015
dc.contributor.authorSarikaya, Ismet
dc.contributor.authorSarikaya, Ali
dc.date.accessioned2024-06-12T11:12:19Z
dc.date.available2024-06-12T11:12:19Z
dc.date.issued2020
dc.departmentTrakya Üniversitesien_US
dc.description.abstractPET imaging, particularly oncologic applications of F-18-FDG, has become a routine diagnostic study. To better describe malignancies, various PET parameters are used. In F-18-FDG PET studies, SUVmax is the most commonly used parameter to measure the metabolic activity of the tumor. In obese patients, SUV corrected by lean body mass (SUL), and in pediatric patients, SUV corrected by body surface area, are recommended. Metabolic tumor volume is an important parameter to determine the local and total tumor burden. Total lesion glycolysis (SUVmean x metabolic tumor volume) provides information about averages. Some treatment response assessment protocols recommend using the SUVpeak or SULpeak of the tumor. Tumor-to-liver ratio and tumor-to-blood-pool ratio are helpful when comparing studies for treatment response assessment. Dual-time-point PET imaging with retention index can help differentiate malignant from benign lesions and may help detect small lesions. Dynamic F-18-FDG PET imaging and quantitative analysis can measure the metabolic, phosphorylation, and dephosphorylation rates of lesions but are mainly used for research purposes. In this article, we will review the currently available PET parameters in F-18-FDG studies with their importance, uses, limitations, and reasons for erroneous results.en_US
dc.identifier.doi10.2967/jnmt.119.236109
dc.identifier.endpage282en_US
dc.identifier.issn0091-4916
dc.identifier.issn1535-5675
dc.identifier.issue3en_US
dc.identifier.pmid31811061en_US
dc.identifier.scopus2-s2.0-85090491441en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage278en_US
dc.identifier.urihttps://doi.org/10.2967/jnmt.119.236109
dc.identifier.urihttps://hdl.handle.net/20.500.14551/23121
dc.identifier.volume48en_US
dc.identifier.wosWOS:000565943700017en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherSoc Nuclear Medicine Incen_US
dc.relation.ispartofJournal Of Nuclear Medicine Technologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectPETen_US
dc.subjectParameteren_US
dc.subjectF-18-FDGen_US
dc.subjectOncologyen_US
dc.subjectSUVen_US
dc.subjectPositron-Emission-Tomographyen_US
dc.subjectStandardized Uptake Valuesen_US
dc.subjectMetabolic Tumor Volumeen_US
dc.subjectTotal Lesion Glycolysisen_US
dc.subjectLean Body-Massen_US
dc.subjectPrognostic Valueen_US
dc.subjectFdg Uptakeen_US
dc.subjectPediatric-Patientsen_US
dc.subjectResponse Criteriaen_US
dc.subjectBreast-Canceren_US
dc.titleAssessing PET Parameters in Oncologic 18F-FDG Studiesen_US
dc.typeArticleen_US

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