Candida arthritis in a patient with chronic myelogenous leukemia (CML) in blastic transformation, unresponsive to fluconazole, but treated effectively with liposomal amphotericin B

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dc.authorwosidTurgut, Burhan/A-2517-2016
dc.contributor.authorTurgut, B
dc.contributor.authorVural, Ö
dc.contributor.authorDemir, M
dc.contributor.authorKaldir, M
dc.date.accessioned2024-06-12T10:55:35Z
dc.date.available2024-06-12T10:55:35Z
dc.date.issued2002
dc.departmentTrakya Üniversitesien_US
dc.description.abstractCandida arthritis is quite rare and might be caused either by direct intra-articular inoculation of Candida or secondary to hematogeneous seeding of Candida in immunocompromised hosts. Until now less than 50 cases of Candida arthritis have been reported in the literature. We report a case of Candida arthritis, which occurred in a patient with chronic myelogenous leukemia (CML) in blastic transformation. Aggressive chemotherapy and broad-spectrum antibiotics for a prolonged period for febrile neutropenia had been given to the patient. Arthritis of the left knee appeared during the recovery phase of leukopenia. Despite treatment with fluconazole, no clinical or microbiological improvement was obtained. Thus, administration of liposomal amphotericin B was started and after 3 days there was improvement. We can conclude that fluconazole might not be sufficient in some Candida arthritis cases and liposomal amphotericin B might be a good alternative in these resistant cases.en_US
dc.identifier.doi10.1007/s00277-002-0503-2
dc.identifier.endpage531en_US
dc.identifier.issn0939-5555
dc.identifier.issue9en_US
dc.identifier.pmid12373355en_US
dc.identifier.scopus2-s2.0-0036942919en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage529en_US
dc.identifier.urihttps://doi.org/10.1007/s00277-002-0503-2
dc.identifier.urihttps://hdl.handle.net/20.500.14551/19480
dc.identifier.volume81en_US
dc.identifier.wosWOS:000179029900008en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherSpringer-Verlagen_US
dc.relation.ispartofAnnals Of Hematologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectCandida Arthritisen_US
dc.subjectChronic Myelogenous Leukemiaen_US
dc.subjectLiposomal Amphotericin Ben_US
dc.subjectAcute Myeloid-Leukemiaen_US
dc.subjectFungal Arthritisen_US
dc.titleCandida arthritis in a patient with chronic myelogenous leukemia (CML) in blastic transformation, unresponsive to fluconazole, but treated effectively with liposomal amphotericin Ben_US
dc.typeArticleen_US

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