The importance of speckle tracking echocardiography in the evaluation of cardiac functions in patients with rheumatoid arthritis
dc.authorid | emmungil, hakan/0000-0001-5184-4404 | |
dc.authorid | EBIK, MUSTAFA/0000-0002-0585-0958 | |
dc.contributor.author | Ebik, Muserref | |
dc.contributor.author | Tastekin, Nurettin | |
dc.contributor.author | Gurdogan, Muhammet | |
dc.contributor.author | Ebik, Mustafa | |
dc.contributor.author | Birtane, Murat | |
dc.contributor.author | Emmungil, Hakan | |
dc.contributor.author | Yilmazer, Baris | |
dc.date.accessioned | 2024-06-12T11:07:30Z | |
dc.date.available | 2024-06-12T11:07:30Z | |
dc.date.issued | 2024 | |
dc.department | Trakya Üniversitesi | en_US |
dc.description.abstract | Objectives: In this study, we aimed to analyze the layer-specific strain values obtained by speckle tracking echocardiography (STE) method in the determination of subclinical cardiac dysfunction in rheumatoid arthritis (RA) patients. Patients and methods: Between February 2019 and October 2019, a total of 63 female RA patients (mean age: 51.82 +/- 6.07 years; range, 40 and 65 years) who had a confirmed diagnosis were included. Thirty-one age-matched female healthy individuals (mean age: 50.71 +/- 5.37 years; range, 40 and 65 years) were selected as the control group. The patients were divided into three groups according to the duration of disease as <5 years, 5-10 years and >10 years. The Disease Activity Score in 28 joint - C-reactive protein (CRP) was used to determine disease activation. The standard assessment included complete serum CRP, anti-cyclic citrullinated peptide, rheumatoid factor, N-terminal pro B-type natriuretic peptide (NT-proBNP), and homocysteine. Global longitudinal strain (GLS) analysis was performed with STE. Results: The NT-proBNP values were found to be higher in RA patients compared to the control group (p=0.044). In terms of conventional echocardiographic parameters, a significant difference between E/A and E/E' ratios was observed (p<0.001 and p=0.015). Endocardium, transmural, and epicardium GLS values obtained by STE were found to be lower in RA patients (p<0.05). The left ventricular (LV) GLS values worsened, as the duration of disease increased (p<0.05). There was a significant correlation between RA disease activity and LV GLS values, showing that increasing levels of disease activity was associated with worse LV GLS (r=0.583, p<0.01 and r=0.681, p<0.01 and r=0.689, p<0.01 for endocardium, transmural and epicardium, respectively). Conclusion: Our study results suggest that the layer-specific GLS values obtained by STE decrease in RA patients. | en_US |
dc.description.sponsorship | Trakya University Scientific Research Projects Unit | en_US |
dc.description.sponsorship | publication Funding: This study was financially supported by the Trakya University Scientific Research Projects Unit. | en_US |
dc.identifier.doi | 10.46497/ArchRheumatol.2024.10274 | |
dc.identifier.issn | 2618-6500 | |
dc.identifier.scopus | 2-s2.0-85194200123 | en_US |
dc.identifier.scopusquality | N/A | en_US |
dc.identifier.uri | https://doi.org/10.46497/ArchRheumatol.2024.10274 | |
dc.identifier.uri | https://hdl.handle.net/20.500.14551/22072 | |
dc.identifier.wos | WOS:001158905500001 | en_US |
dc.identifier.wosquality | N/A | en_US |
dc.indekslendigikaynak | Web of Science | en_US |
dc.indekslendigikaynak | Scopus | en_US |
dc.language.iso | en | en_US |
dc.publisher | Turkish League Against Rheumatism | en_US |
dc.relation.ispartof | Archives Of Rheumatology | en_US |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |
dc.rights | info:eu-repo/semantics/openAccess | en_US |
dc.subject | Layer Specific Global Longitudinal Strain | en_US |
dc.subject | Rheumatoid Arthritis | en_US |
dc.subject | Speckle Tracking Echocardiography | en_US |
dc.subject | Heart-Failure | en_US |
dc.subject | Association | en_US |
dc.subject | Dysfunction | en_US |
dc.subject | Disease | en_US |
dc.title | The importance of speckle tracking echocardiography in the evaluation of cardiac functions in patients with rheumatoid arthritis | en_US |
dc.type | Article | en_US |