The relationship between positivity for COVID-19 RT-PCR and symptoms, clinical findings, and mortality in Turkey

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dc.authoridakpinar, yunus/0000-0001-5216-6289
dc.authoridBorku Uysal, Betul/0000-0001-9292-5024
dc.authoridCengiz, Mahir/0000-0003-3343-8650
dc.authorwosidakpinar, yunus/JDW-2741-2023
dc.authorwosidŞahin Yavuzer, Serap/ABH-2784-2021
dc.authorwosidYavuzer, Hakan/Y-5492-2018
dc.authorwosidBorku Uysal, Betul/AAZ-8155-2021
dc.authorwosidİkitimur, Hande/KJL-4127-2024
dc.authorwosidIslamoglu, Mehmet Sami/ABH-2138-2021
dc.authorwosidCengiz, Mahir/A-6417-2019
dc.contributor.authorOzcan, Erkan
dc.contributor.authorYavuzer, Serap
dc.contributor.authorBorku Uysal, Betul
dc.contributor.authorIslamoglu, Mehmet Sami
dc.contributor.authorIkitimur, Hande
dc.contributor.authorUnal, Omer Faruk
dc.contributor.authorAkpinar, Yunus Emre
dc.date.accessioned2024-06-12T10:58:50Z
dc.date.available2024-06-12T10:58:50Z
dc.date.issued2021
dc.departmentTrakya Üniversitesien_US
dc.description.abstractIntroduction: This study aimed to assess the correlation between nucleic acid amplification test (real-time reverse transcription-polymerase chain reaction, RT-PCR) positivity of patients presenting with suspected COVID-19 and pneumonic infiltration consistent with COVID-19-specific pneumonia diagnosis on thoracic computed tomography (CT), with symptoms, laboratory findings, and clinical progression. Methods: The study included 286 patients (female:male 131:155; mean age, 53.3 +/- 17.9 years) who were divided into two groups according to their RT-PCR test results. The symptoms, laboratory examinations, clinical findings, and thoracic CT imaging of the patients were evaluated. Results: While the physical examination, comorbidities, and total CT scores were similar between the groups, taste/smell abnormalities were observed more frequently in the PCR-positive group. The use of moxifloxacin, lopinavir/ritonavir, and tocilizumab was higher in the PCR-positive group (p = 0.016, p < 0.001, and p = 0.002, respectively). The duration of hospitalization, intensive care requirement, and mortality rate of the studied groups did not differ between the groups. Conclusions: Among patients presenting with suspected COVID-19 and pneumonic infiltration consistent with COVID-19 on thoracic CT, the symptoms, physical examination, total CT scores, duration of hospitalization, intensive care requirement, and mortality rate were similar between RT-PCR-positive and RT-PCR-negative patients. However, PCR-positive patients appeared to require more specific treatments.en_US
dc.identifier.doi10.1080/14737159.2021.1882305
dc.identifier.endpage250en_US
dc.identifier.issn1473-7159
dc.identifier.issn1744-8352
dc.identifier.issue2en_US
dc.identifier.pmid33496627en_US
dc.identifier.scopus2-s2.0-85100809905en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage245en_US
dc.identifier.urihttps://doi.org/10.1080/14737159.2021.1882305
dc.identifier.urihttps://hdl.handle.net/20.500.14551/20189
dc.identifier.volume21en_US
dc.identifier.wosWOS:000616227400001en_US
dc.identifier.wosqualityQ1en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherTaylor & Francis Asen_US
dc.relation.ispartofExpert Review Of Molecular Diagnosticsen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectCOVID-19en_US
dc.subjectSARS Cov-2en_US
dc.subjectCOVID-19 RT-PCRen_US
dc.subjectPneumoniaen_US
dc.subjectCten_US
dc.titleThe relationship between positivity for COVID-19 RT-PCR and symptoms, clinical findings, and mortality in Turkeyen_US
dc.typeArticleen_US

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