Fear of movement-related pain disturbs cortical preparatory activity after becoming aware of motor intention

Basit Öğe Kaydı
dc.authoridNobusako, Satoshi/0000-0001-7183-5054
dc.authoridMorioka, Shu/0000-0003-2853-1789
dc.authorwosidNobusako, Satoshi/KFR-5340-2024
dc.contributor.authorOsumi, Michihiro
dc.contributor.authorSumitani, Masahiko
dc.contributor.authorNishi, Yuki
dc.contributor.authorNobusako, Satoshi
dc.contributor.authorDilek, Burcu
dc.contributor.authorMorioka, Shu
dc.date.accessioned2024-06-12T10:54:06Z
dc.date.available2024-06-12T10:54:06Z
dc.date.issued2021
dc.departmentTrakya Üniversitesien_US
dc.description.abstractFear of movement-related pain is known to disturb the process of motor preparation in patients with chronic pain. In the present study, we aimed to clarify the neural mechanisms underlying the influence of fear movementrelated pain on motor preparatory brain activity using Libet's clock and electroencephalography (EEG). Healthy participants were asked to press a button while watching a rotating Libet's clock-hand, and report the number on the clock (W time) when they made the decision to press the button with their right index finger. Immediately after pressing the button, a painful electrical stimulus was delivered to the dorsum of the left hand, causing participants to feel fear of movement (button press-related pain). We found that fear of movementrelated pain caused the W time to be early, and that the amplitudes of readiness potentials (RPs) increased after awareness of motor intention emerged. In addition, fear of movement-related pain caused over-activation of the medial frontal cortex, supplementary motor area, cingulate motor area, and primary motor cortex after participants became aware of their motor intention. Such over-activation might result from conflict between the unrealized desire to escape from a painful experience and motivation to perform a required motor task.en_US
dc.description.sponsorshipJSPS KAKENHI Grant [20K11249]; Grants-in-Aid for Scientific Research [20K11249] Funding Source: KAKENen_US
dc.description.sponsorshipThis study was supported by a grant from JSPS KAKENHI Grant Numbers 20K11249. We thank Benjamin Knight, MSc., and Sydney Koke, MFA, from Edanz Group (https://jp.edanz.com /ac) for editing a draft of this manuscript.en_US
dc.identifier.doi10.1016/j.bbr.2021.113379
dc.identifier.issn0166-4328
dc.identifier.issn1872-7549
dc.identifier.pmid34051229en_US
dc.identifier.urihttps://doi.org/10.1016/j.bbr.2021.113379
dc.identifier.urihttps://hdl.handle.net/20.500.14551/18918
dc.identifier.volume411en_US
dc.identifier.wosWOS:000667211600007en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherElsevieren_US
dc.relation.ispartofBehavioural Brain Researchen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectAwarenessen_US
dc.subjectEEGen_US
dc.subjectSloretaen_US
dc.subjectPainen_US
dc.subjectReadiness Potentialen_US
dc.subjectElectromagnetic Tomography Loretaen_US
dc.subjectContingent Negative-Variationen_US
dc.subjectSource Localizationen_US
dc.subjectEegen_US
dc.subjectPotentialsen_US
dc.subjectCortexen_US
dc.subjectLimben_US
dc.subjectConsequencesen_US
dc.subjectExpectancyen_US
dc.subjectAvoidanceen_US
dc.titleFear of movement-related pain disturbs cortical preparatory activity after becoming aware of motor intentionen_US
dc.typeArticleen_US

Dosyalar

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
PubMed İndeksli Yayınlar Koleksiyonu