Approach to drug allergies in the childhood

dc.authorwosidYazicioglu, Mehtap/AAB-9587-2022
dc.contributor.authorYazicioglu, Mehtap
dc.date.accessioned2024-06-12T10:56:15Z
dc.date.available2024-06-12T10:56:15Z
dc.date.issued2014
dc.departmentTrakya Üniversitesien_US
dc.description.abstractDrug reactions (DR) are adverse admissions or harmful effects of drugs. They constitute 6.5% of all hospital admission. DR develops with a rate of 15% in patients who are treated by hospitalization. The possibility of DR should be considered in the differential diagnosis when any medical problem occurs in a person who uses medication. Detailed history and physical examination are directive in differentiation if the reaction is a result of immune mechanisms. Although diagnostic tests are limited, they are beneficial according to the effective immune mechanism and presence of organ-specific or systemic findings. In children, the major difficulty in the diagnosis of DR is differentiation of maculopapular drug eruptions from viral exanthem which is observed very commonly in this age group. In treatment of allergic reactions, the first step is to immediately discontinue the responsible drug. Avoidance of using over-the-counter drugs and use of drugs orally if possible are important in terms of prevention of drug allergies. Cross-reactivity between drugs with similar structure should be considered when choosing an alternative drug. If an alternative drug or a drug which would not lead to cross-reaction can not be found, the drug is administered by desensitization. In this article, the apporach to drug allergies in children will be evaluated in accordance with current guidelines.en_US
dc.identifier.doi10.5152/tpa.2014.1944
dc.identifier.endpage103en_US
dc.identifier.issn1306-0015
dc.identifier.issn1308-6278
dc.identifier.issue2en_US
dc.identifier.pmid26078643en_US
dc.identifier.scopus2-s2.0-84901291802en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage99en_US
dc.identifier.urihttps://doi.org/10.5152/tpa.2014.1944
dc.identifier.urihttps://hdl.handle.net/20.500.14551/19726
dc.identifier.volume49en_US
dc.identifier.wosWOS:000422391600002en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isotren_US
dc.publisherAvesen_US
dc.relation.ispartofTurk Pediatri Arsivi-Turkish Archives Of Pediatricsen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectChilden_US
dc.subjectDrug Allergyen_US
dc.subjectDiagnosisen_US
dc.subjectTreatmenten_US
dc.subjectApproachen_US
dc.titleApproach to drug allergies in the childhooden_US
dc.typeArticleen_US

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