Spontaneous otoacoustic emission recordings during contralateral pure-tone activation of medial olivocochlear reflex
Küçük Resim Yok
Tarih
2017
Yazarlar
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Akademiai Kiado Rt
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
We hypothesized that cochlear frequency discrimination occurs through medial olivocochlear efferent (MOCE)-induced alterations in outer hair cell (OHC) electromotility, which is independent from basilar membrane traveling waves. After obtaining informed consent, volunteers with normal hearing (n = 10; mean age: 20.6 +/- 1.2 years) and patients with unilateral deafness (n = 10; mean age: 30.2 +/- 17.9 years) or bilateral deafness (n = 8; mean age: 30.7 +/- 13.8 years) underwent a complete physical and audiological examination, and audiological tests including transient evoked otoacoustic emission and spontaneous otoacoustic emission (TEOAE and SOAE, respectively). SOAE recordings were performed during contralateral pure-tone stimuli at 1 and 3 kHz. SOAE recordings in the presence of contralateral pure-tone stimuli showed frequency-specific activation out of the initial frequency range of SOAE responses. Basilar membrane motion during pure-tone stimulation results from OHC activation by means of MOCE neurons rather than from a traveling wave. Eventually, frequency-specific responses obtained from SOAEs suggested that OHC electromotility may be responsible for frequency discrimination of the cochlea independently from basilar membrane motion.
Açıklama
Anahtar Kelimeler
Otoacoustic Emissions, Spontaneous, Hair Cells, Auditory, Outer, Cochlea, Audiometry, Pure-Tone, Medial Olivocochlear Efferents, Outer Hair-Cells, Cochlear Amplification, Mammalian Cochlea, Motor Protein, Prestin, Stimulation, Mechanics, Molecules, Motion, Corti
Kaynak
Physiology International
WoS Q Değeri
Q4
Scopus Q Değeri
Q3
Cilt
104
Sayı
2
