Poisoning severity score, Glasgow coma scale, corrected QT interval in acute organophosphate poisoning

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dc.authoridkavalcı, cemil/0000-0003-2529-2946
dc.authoridOzkan, Seda/0000-0003-1835-8820
dc.authoridikizceli, ibrahim/0000-0002-9825-4716
dc.authoridAKDUR, OKHAN/0000-0003-3099-6876
dc.authorwosidkavalcı, cemil/AGG-1308-2022
dc.authorwosidOzkan, Seda/AAE-8598-2019
dc.authorwosidikizceli, ibrahim/D-1981-2019
dc.authorwosidAKDUR, OKHAN/A-1913-2019
dc.contributor.authorAkdur, Okhan
dc.contributor.authorDurukan, Polat
dc.contributor.authorOzkan, Seda
dc.contributor.authorAvsarogullari, Levent
dc.contributor.authorVardar, Alper
dc.contributor.authorKavalci, Cemil
dc.contributor.authorIkizceli, Ibrahim
dc.date.accessioned2024-06-12T10:56:39Z
dc.date.available2024-06-12T10:56:39Z
dc.date.issued2010
dc.departmentTrakya Üniversitesien_US
dc.description.abstractThe aim of this study was to investigate effectiveness of the poisoning severity score (PSS), Glasgow coma scale (GCS), and corrected QT (QTc) interval in predicting outcomes in acute organophosphates (OP) poisoning. Over a period of 2 years, 62 patients with OP poisoning were admitted to emergency department (ED) of Erciyes University Medical School Hospital. The age, sex, cause of contact, compound involved, time elapsed between exposure and admission to the ED, duration of hospital stay, and cardiac manifestations at the time of presentation were recorded. GCS and poisoning severity score (PSS) was calculated for each patient. Electrocardiogram (ECG) analysis included the rate, rhythm, ST-T abnormalities, conduction defects, and measurement of PR and QT intervals. Sixty-two patients with OP poisoning presented to our ED from January 2007 to December 2008 from which 54 patients were included in the study. The mean age was 34.1 +/- 14.8 years. Of the cases, 53.7% were female. Twenty-six patients had a prolonged QTc interval. Mean PSS of men and women was 1.8 +/- 1.0. No statistically significant correlation was found between the PSS and QTc intervals of the cases. A significant correlation was determined between the GCS and PSS of grade 3 and grade 4 cases. GCS is a parameter that helps clinician to identify advanced grade OP poisoning patients in the initial assessment in the ED. However, ECG findings, such as prolonged QTc interval, are not effective in determination of short-term prognosis and show no relationship with PSS.en_US
dc.identifier.doi10.1177/0960327110364640
dc.identifier.endpage425en_US
dc.identifier.issn0960-3271
dc.identifier.issn1477-0903
dc.identifier.issue5en_US
dc.identifier.pmid20203133en_US
dc.identifier.scopus2-s2.0-77951149880en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage419en_US
dc.identifier.urihttps://doi.org/10.1177/0960327110364640
dc.identifier.urihttps://hdl.handle.net/20.500.14551/19875
dc.identifier.volume29en_US
dc.identifier.wosWOS:000276552600009en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherSage Publications Ltden_US
dc.relation.ispartofHuman & Experimental Toxicologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectClinical Toxicologyen_US
dc.subjectOrganophosphatesen_US
dc.subjectPoisoningen_US
dc.subjectProlongationen_US
dc.subjectManagementen_US
dc.subjectTorsadeen_US
dc.subjectPointesen_US
dc.titlePoisoning severity score, Glasgow coma scale, corrected QT interval in acute organophosphate poisoningen_US
dc.typeArticleen_US

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