Mean platelet volume and peripheral blood count response in acute ischemic stroke

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dc.authoridGULDIKEN, Baburhan/0000-0002-9006-1880
dc.contributor.authorGuldiken, Baburhan
dc.contributor.authorOzkan, Hulya
dc.contributor.authorKabayel, Levent
dc.date.accessioned2024-06-12T11:15:42Z
dc.date.available2024-06-12T11:15:42Z
dc.date.issued2008
dc.departmentTrakya Üniversitesien_US
dc.description.abstractObjectives: Mean platelet volume (MPV) is a marker of the platelet activity and is reported to increase in vascular diseases. The aim of the study is to investigate the relationship between MPV and the subtypes of acute ischemic stroke. Patients and Methods: The patient group consisted of 102 acute ischemic stroke patients who were divided into the large vessel (n=43) and the small vessel (n=59) disease subgroups. Their MPV values were compared with those of 48 age/sex-matched healthy individuals. The relationship of MPV with the subtypes and severity of stroke, and other hematological parameters (platelet count, platecrit, hemoglobin, hematocrit, erythrocyte count, mean corpuscular volume, leukocyte, neutrophil, lymphocyte, monocyte) was further investigated. Results: No difference was found in terms of MPV values between the patient subgroups and control group, and no relation was found between MPV and stroke severity and other hematological parameters (p>0.05). A significant increase in the leukocyte and neutrophil count was seen in patients of the large vessel disease group when compared with the small vessel disease and control group (p<0.005). Neutrophil count is found to be a risk factor for the stroke severity (beta=0.362, p=0.01, OR=1.437, Cl %95 0.02-0.08). Conclusion: No significant change in MPV was seen in acute ischemic stroke. High leukocyte and neutrophil levels are markers for the large vessel disease subtype and severity of ischernic stroke.en_US
dc.identifier.endpage135en_US
dc.identifier.issn1301-3149
dc.identifier.issue2en_US
dc.identifier.scopus2-s2.0-70349131620en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage130en_US
dc.identifier.urihttps://hdl.handle.net/20.500.14551/24038
dc.identifier.volume25en_US
dc.identifier.wosWOS:000258242400008en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isotren_US
dc.publisherAves Yayincilik, Ibrahim Karaen_US
dc.relation.ispartofTrakya Universitesi Tip Fakultesi Dergisien_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectStrokeen_US
dc.subjectMean Platelet Volumeen_US
dc.subjectLeukocyteen_US
dc.subjectNeutrophilen_US
dc.subjectCerebral-Ischemiaen_US
dc.subjectPolymorphonuclear Leukocytesen_US
dc.subjectMyocardial-Infarctionen_US
dc.subjectOxidative Stressen_US
dc.subjectVascular-Diseaseen_US
dc.subjectSizeen_US
dc.subjectNeutrophilsen_US
dc.subjectAggregationen_US
dc.subjectReperfusionen_US
dc.subjectContributeen_US
dc.titleMean platelet volume and peripheral blood count response in acute ischemic strokeen_US
dc.typeArticleen_US

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