Exacerbations of Graves' disease after unilateral adrenalectomy for Cushing's syndrome

Basit Öğe Kaydı
dc.contributor.authorArikan, E
dc.contributor.authorGuldiken, S
dc.contributor.authorAltun, BU
dc.contributor.authorKara, M
dc.contributor.authorTugrul, A
dc.date.accessioned2024-06-12T11:02:49Z
dc.date.available2024-06-12T11:02:49Z
dc.date.issued2004
dc.departmentTrakya Üniversitesien_US
dc.description.abstractCushing's syndrome is characterized by endogenously increased production of glucocorticoids. The activity of immune system is regulated mainly by two systems in the body. Glucocorticoids and NF-kappaB counteract the effects of each other on the immune system. It has been reported that immune response is exaggerated after the amelioration of Cushing's syndrome. We report a rare case of exacerbation of Graves' disease after unilateral adrenalectomy for Cusing's syndrome. A 50-yr-obese woman with hypertension, dyslipidemia, impaired glucose tolerance and insulin resistance was admitted to outpatients clinic of endocrinology. The results of evaluation of glucocorticoids metabolism and adrenal magnetic resonance imaging revealed the Cusing's syndrome. We also assessed thyroid function tests because of the diagnosis of golter and thyroid hormone replacement in her medical history, and the presence of exophthalmia and tachycardia in examination. Althoug TSH level was detected at the lower border of normal range, free T-4 and free T-3 were in normal range and autoantibody of thyroidal peroxidase and thyroglobulin was higer than normal reference range. An operation was performed and a mass was removed from her left adrenal gland. The pathologic examination confirmed adrenal adenoma. She was re-admitted to the outpatient clinic 9 months after with complaints of palpitation, malaise and weight loss. Tests carried out to determine the thyroid function revealed Graves' disease. We prescribed propylthiouracil and P-blocker treatment. (C) 2004, Editrice Kurtis.en_US
dc.identifier.doi10.1007/BF03347482
dc.identifier.endpage576en_US
dc.identifier.issn0391-4097
dc.identifier.issue6en_US
dc.identifier.pmid15717657en_US
dc.identifier.scopus2-s2.0-4544321124en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage574en_US
dc.identifier.urihttps://doi.org/10.1007/BF03347482
dc.identifier.urihttps://hdl.handle.net/20.500.14551/21420
dc.identifier.volume27en_US
dc.identifier.wosWOS:000223734300012en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherEditrice Kurtis S R Len_US
dc.relation.ispartofJournal Of Endocrinological Investigationen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectGraves' Diseaseen_US
dc.subjectCushing's Syndromeen_US
dc.subjectAutoimmunityen_US
dc.subjectRheumatoid-Arthritisen_US
dc.subjectAdenomaen_US
dc.subjectAxisen_US
dc.titleExacerbations of Graves' disease after unilateral adrenalectomy for Cushing's syndromeen_US
dc.typeArticleen_US

Dosyalar

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
PubMed İndeksli Yayınlar Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu