The evaluation of the median nerve in subclinical hypothyroidism by high-resolution sonography

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dc.contributor.authorArikan, E
dc.contributor.authorPekindil, G
dc.contributor.authorGuldiken, S
dc.contributor.authorPekindil, Y
dc.date.accessioned2024-06-12T11:15:45Z
dc.date.available2024-06-12T11:15:45Z
dc.date.issued2005
dc.departmentTrakya Üniversitesien_US
dc.description.abstractThe aim of this study is to evaluate whether subclinical hypothyroidism causes any alteration of the median nerve diameters by using sonography, and whether L-thyroxine treatment can improve the median nerve dimensions. Twenty-two female patients with subclinical hypothyroidism participated in this study. All patients were asked for the manifestations of carpal tunnel syndrome. They were examined and nerve conduction tests were performed. Right and left median nerve measurements (major and minor axis and cross-sectional area) were determined in all patients by high-resolution sonography before and after euthyroidism was achieved with L-thyroxine treatment. All sonographic measurements were within normal limits in 18 of 22 cases. Four patients had increased the measurements of the median nerve, but only 2 cases of 4 had increased cross-sectional area of median nerve and one of them had clinical symptoms simulating carpal tunnel syndrome. None of them has positive clinical signs of carpal tunnel syndrome. Nerve conduction velocities did not indicate carpal tunnel syndrome in patients with subclinical hypothyroidism. L-thyroxine treatment significantly decreased the mean cross-sectional area, minor and major axes of the right and left median nerves. Clinical symptoms were gradually improved. There was no correlation between the measurement of median nerve and thyroid hormones, thyroid-stimulating hormone, body mass index, and age. The duration of treatment with L-T-4 and dose did not correlate with the measurement of the median nerve. This study shows that subclinical hypothyroidism causes some alterations in the median nerve diameters in a few patients. L-Thyroxine replacement in subclinical hypothyroidism decreases the measurements of the median nerve.en_US
dc.identifier.doi10.1097/01.ten.0000170837.53508.61
dc.identifier.endpage212en_US
dc.identifier.issn1051-2144
dc.identifier.issn1539-9192
dc.identifier.issue4en_US
dc.identifier.scopus2-s2.0-23244440918en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage209en_US
dc.identifier.urihttps://doi.org/10.1097/01.ten.0000170837.53508.61
dc.identifier.urihttps://hdl.handle.net/20.500.14551/24063
dc.identifier.volume15en_US
dc.identifier.wosWOS:000230875400005en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherLippincott Williams & Wilkinsen_US
dc.relation.ispartofEndocrinologisten_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectSubclinical Hypothyroidismen_US
dc.subjectCarpal Tunnel Syndromeen_US
dc.subjectMedian Nerveen_US
dc.subjectSonographyen_US
dc.subjectCarpal-Tunnel-Syndromeen_US
dc.subjectNeuromuscular Findingsen_US
dc.subjectThyroid-Dysfunctionen_US
dc.subjectThyroxine Therapyen_US
dc.subjectPeripheral-Nervesen_US
dc.subjectPolyneuropathyen_US
dc.subjectDiagnosisen_US
dc.subjectReplacementen_US
dc.subjectConductionen_US
dc.titleThe evaluation of the median nerve in subclinical hypothyroidism by high-resolution sonographyen_US
dc.typeArticleen_US

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