Serum Prealbumin: a potential predictor of Right Ventricular Dysfunction in patients receiving programmed hemodialysis

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dc.authoridGök, Murat/0000-0003-3118-9064
dc.authoridTAYLAN, GOKAY/0000-0002-7015-4537
dc.authoridISIKTAS SAYILAR, EMEL/0000-0002-8824-6560
dc.authorwosidGök, Murat/AAZ-3324-2021
dc.authorwosidTAYLAN, GOKAY/HJZ-4693-2023
dc.authorwosidisiktas sayilar, emel/W-2575-2017
dc.contributor.authorGok, Murat
dc.contributor.authorKurtul, Alparslan
dc.contributor.authorTaylan, Gokay
dc.contributor.authorSayilar, Emel Isiktas
dc.contributor.authorYalta, Kenan
dc.date.accessioned2024-06-12T11:03:06Z
dc.date.available2024-06-12T11:03:06Z
dc.date.issued2022
dc.departmentTrakya Üniversitesien_US
dc.description.abstractOBJECTIVE: Prealbumin has been a reliable marker to predict protein energy malnutrition and hypercatabolic state. In this analysis, we particularly aimed to investigate the potential association between serum prealbumin levels and right ventricular dysfunction in patients receiving programmed hemodialysis. METHODS: A total of 57 subjects were included in the analysis. The subjects were then categorized into two groups: right ventricular dysfunction (n=18) and non-right ventricular dysfunction (n=39) groups. In all patients, detailed transthoracic echocardiography (following hemodialysis) were performed along with the evaluation of complete blood count, routine biochemistry parameters, and, in particular, serum prealbumin levels. RESULTS: Mortality rate at 3 years was found to be significantly higher in the right ventricular dysfunction group (p=0.042). Serum prealbumin levels were also significantly lower in the right ventricular dysfunction group compared with the non-right ventricular dysfunction group (23.83??8.50 mg/dL versus 31.38??6.81 mg/dL, p=0.001). In the receiver operating characteristics curve analysis, a prealbumin cutoff value of <28.5 mg/dL was found to predict right ventricular dysfunction, with a sensitivity of 67% and a specificity of 62% (area under the curve: 0.744). In the correlation analysis, a moderate yet significant positive correlation was demonstrated between serum prealbumin and tricuspid annular plane systolic excursion (r=0.365, p=0.005). CONCLUSION: This study suggests that low serum prealbumin might serve as a potential predictor of right ventricular dysfunction (and its clinical consequences) in patients receiving programmed hemodialysis.en_US
dc.identifier.doi10.1590/1806-9282.20211348
dc.identifier.endpage796en_US
dc.identifier.issn1806-9282
dc.identifier.issue6en_US
dc.identifier.pmid35766693en_US
dc.identifier.scopus2-s2.0-85133214911en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage792en_US
dc.identifier.urihttps://doi.org/10.1590/1806-9282.20211348
dc.identifier.urihttps://hdl.handle.net/20.500.14551/21532
dc.identifier.volume68en_US
dc.identifier.wosWOS:000823735900017en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherAssoc Medica Brasileiraen_US
dc.relation.ispartofRevista Da Associacao Medica Brasileiraen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectHemodialysisen_US
dc.subjectMalnutritionen_US
dc.subjectPrealbuminen_US
dc.subjectMortalityen_US
dc.subjectRight Ventricular Dysfunctionsen_US
dc.subjectInflammation-Atherosclerosis Syndromeen_US
dc.subjectNutritional-Statusen_US
dc.subjectPrognostic Valueen_US
dc.subjectRenal-Failureen_US
dc.subjectMalnutritionen_US
dc.subjectMortalityen_US
dc.titleSerum Prealbumin: a potential predictor of Right Ventricular Dysfunction in patients receiving programmed hemodialysisen_US
dc.typeArticleen_US

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