Comparison between semiquantitative interictal Tc-99m HMPAO SPECT and clinical parameters in children with partial seizures

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dc.authoridDURMUS ALTUN, GULAY/0000-0002-1822-9386
dc.authorwosidDURMUS ALTUN, GULAY/S-6586-2016
dc.contributor.authorSarikaya, A
dc.contributor.authorKaya, M
dc.contributor.authorKarasalihoglu, S
dc.contributor.authorAlemdar, A
dc.contributor.authorAltun, G
dc.contributor.authorBerkarda, S
dc.date.accessioned2024-06-12T11:14:10Z
dc.date.available2024-06-12T11:14:10Z
dc.date.issued1999
dc.departmentTrakya Üniversitesien_US
dc.description.abstractThe aim of the present study was to correlate between clinical parameters (age, age of onset, frequency and durationof seizures) and semiquantitative interictal SPECT parameters in children with partial seizures. We obtained 30 patients who had hypoperfusion in interictal SPECT, retrospectively. All patients underwent a detailed clinical examination, electroencephalography (EEG) investigation and brain computerized tomography (CT) and/or magnetic resonance imaging (MRI). Single photon emission computerized tomography (SPECT) studies were evaluated visually and by calculating semiquantitative parameters (the degree (asymmetry index, Al) and extent (number of ROI) of hypoperfusion). Visual analysis detected ipsilateral hypoperfusion in 23 (76%) patients with a unilateral focus and contralateral hypoperfusion in seven patients. We found an inverse correlation between the age at onset of seizure (r = -0.40, P = 0.025), frequency of seizures(but positive correlation; r = 0.77, P = 0.000) and AI. Number of ROIs showed a moderate correlation with the frequency of seizures (r = 0.67, P = 0.000), while correlation of the age at onset of seizures was not significant. This study per-formed in pediatric patients also suggested that either SPECT parameters may be used for correlating with clinical parameters. (C) 1999 Elsevier Science B.V. All rights reserved.en_US
dc.identifier.doi10.1016/S0387-7604(99)00002-9
dc.identifier.endpage183en_US
dc.identifier.issn0387-7604
dc.identifier.issue3en_US
dc.identifier.pmid10372904en_US
dc.identifier.scopus2-s2.0-0032967258en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage179en_US
dc.identifier.urihttps://doi.org/10.1016/S0387-7604(99)00002-9
dc.identifier.urihttps://hdl.handle.net/20.500.14551/23827
dc.identifier.volume21en_US
dc.identifier.wosWOS:000080451500007en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherElsevier Science Bven_US
dc.relation.ispartofBrain & Developmenten_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectSingle Photon Emission Computerized Tomographyen_US
dc.subjectEpilepsyen_US
dc.subjectSemiquantitativeen_US
dc.subjectTemporal-Lobe Epilepsyen_US
dc.subjectCerebral Blood-Flowen_US
dc.subjectEmission Computed-Tomographyen_US
dc.subjectGlucose-Metabolismen_US
dc.subjectTechnetium-99m-Hmpaoen_US
dc.subjectPerfusionen_US
dc.subjectPeten_US
dc.titleComparison between semiquantitative interictal Tc-99m HMPAO SPECT and clinical parameters in children with partial seizuresen_US
dc.typeArticleen_US

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