Spectroscopic studies on the antioxidant activity of ellagic acid

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dc.authoridKilic, ismail/0000-0002-3270-063X
dc.authorwosidKilic, ismail/I-5823-2019
dc.contributor.authorKilic, Ismail
dc.contributor.authorYesiloglu, Yesim
dc.contributor.authorBayrak, Yuksel
dc.date.accessioned2024-06-12T11:00:13Z
dc.date.available2024-06-12T11:00:13Z
dc.date.issued2014
dc.departmentTrakya Üniversitesien_US
dc.description.abstractEllagic acid (EA, C14H6O8) is a natural dietary polyphenol whose benefits in a variety of diseases shown in epidemiological and experimental studies involve anti-inflammation, anti-proliferation, anti-angiogenesis, anticarcinogenesis and anti-oxidation properties. In vitro radical scavenging and antioxidant capacity of EA were clarified using different analytical methodologies such as total antioxidant activity determination by ferric thiocyanate, hydrogen peroxide scavenging, 1,1-diphenyl-2-picryl-hydrazyl free radical (DPPH) scavenging, 2,2'-azino-bis(3-ethylbenzthiazoline-6-sulfonic acid) (ABTS) radical scavenging activity and superoxide anion radical scavenging, ferrous ions (Fe2+) chelating activity and ferric ions (Fe3+) reducing ability. EA inhibited 71.2% lipid peroxidation of a linoleic acid emulsion at 45 mu g/mL concentration. On the other hand, butylated hydroxytoluene (BHT), butylated hydroxyanisole (BHA), alpha-tocopherol and ascorbic acid displayed 69.8%, 66.8%, 64.5% and 59.7% inhibition on the peroxidation of linoleic acid emulsion at the same concentration, respectively. In addition, EA had an effective DPPH center dot scavenging, ABTS(center dot+) scavenging, superoxide anion radical scavenging, hydrogen peroxide scavenging, ferric ions (Fe3+) reducing power and ferrous ions (Fe2+) chelating activities. Also, those various antioxidant activities were compared to BHA, BHT, alpha-tocopherol and ascorbic acid as references antioxidant compounds. These results' suggested that EA can be used in the pharmacological, food industry and medicine because of these properties. (C) 2014 Elsevier B.V. All rights reserved.en_US
dc.identifier.doi10.1016/j.saa.2014.04.052
dc.identifier.endpage452en_US
dc.identifier.issn1386-1425
dc.identifier.pmid24813273en_US
dc.identifier.scopus2-s2.0-84899807705en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage447en_US
dc.identifier.urihttps://doi.org/10.1016/j.saa.2014.04.052
dc.identifier.urihttps://hdl.handle.net/20.500.14551/20751
dc.identifier.volume130en_US
dc.identifier.wosWOS:000338806800059en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherPergamon-Elsevier Science Ltden_US
dc.relation.ispartofSpectrochimica Acta Part A-Molecular And Biomolecular Spectroscopyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectEllagic Aciden_US
dc.subjectMetal Chelatingen_US
dc.subjectAntioxidant Activityen_US
dc.subjectReducing Poweren_US
dc.subjectFree Radicalsen_US
dc.subjectIn-Vitro Antioxidanten_US
dc.subjectDerivativesen_US
dc.subjectExtractsen_US
dc.titleSpectroscopic studies on the antioxidant activity of ellagic aciden_US
dc.typeArticleen_US

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