Factors affecting haemorrhagic transformation in middle cerebral artery infarctions

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dc.contributor.authorÇelik, Y
dc.contributor.authorUtku, U
dc.contributor.authorAsil, T
dc.contributor.authorBalci, K
dc.date.accessioned2024-06-12T11:17:30Z
dc.date.available2024-06-12T11:17:30Z
dc.date.issued2004
dc.departmentTrakya Üniversitesien_US
dc.description.abstractObjective: Haemorrhagic transformation (HT) affects treatment and prognosis in patients with acute ischaemic stroke. The factors affecting haemorrhagic transformation in infarcts due to occlusion of middle cerebral artery (MCA) stem or branch were investigated. Materials and methods: Of 412 patients who were followed in our clinic between January 2001 and December 2001 with acute ischaemic stroke, 86 patients with occlusion in MCA stem or branch were enrolled in this study. These patients were divided into 2 groups, those with HT (n = 35) and without HT (n = 51). Age, sex, systemic arterial hypertension, diabetes mellitus, blood glucose level in the acute period, renal and liver function tests, systolic and diastolic arterial blood pressure in the acute period, previous cerebrovascular disease, leukoaraiosis, modified Rankin Disability Score (mRDS) and stroke subtype were evaluated. Results: High blood glucose level in the acute period and presence of leukoaraiosis on cranial computerized (CCT) tomography were detected as risk factors in development of HT. HT was seen more frequently in MCA stem infarction than branch infarction. mRDS were worse in the group with HT. In multivariate analysis, there were independent relationships between mean blood glucose level on admission, mRDS, presence of diabetes mellitus, and MCA stem infarction and development of haemorrhagic transformation in patients with MCA territorial infarction. (C) 2003 Elsevier Ltd. All rights reserved.en_US
dc.identifier.doi10.1016/j.jocn.2003.08.001
dc.identifier.endpage658en_US
dc.identifier.issn0967-5868
dc.identifier.issue6en_US
dc.identifier.pmid15261244en_US
dc.identifier.scopus2-s2.0-3142663170en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage656en_US
dc.identifier.urihttps://doi.org/10.1016/j.jocn.2003.08.001
dc.identifier.urihttps://hdl.handle.net/20.500.14551/24730
dc.identifier.volume11en_US
dc.identifier.wosWOS:000224845000021en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherChurchill Livingstoneen_US
dc.relation.ispartofJournal Of Clinical Neuroscienceen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectAcute Ischemic-Strokeen_US
dc.subjectTissue-Plasminogen Activatoren_US
dc.subjectCooperative Acute Strokeen_US
dc.subjectGlucose Levelen_US
dc.subjectPredictorsen_US
dc.subjectRisken_US
dc.titleFactors affecting haemorrhagic transformation in middle cerebral artery infarctionsen_US
dc.typeArticleen_US

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