Breast cyst fluid plasmin activity and its effect on TGF-?2 activation
Küçük Resim Yok
Tarih
2008
Yazarlar
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Taylor & Francis Inc
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
There are two types of breast cyst and women with apocrine breast cyst may have a higher risk of developing breast cancer than cyst lined by flattened epithelium. Transforming growth factor-beta's growth inhibitory effect on epithelial cells suggests a potential protective role in breast cancer. The aim of this study was to investigate the presence of plasmin in both breast cyst groups and the possible role of plasmin on transforming growth factor beta activation. Presence of high plasmin level may indicate its importance on activation process, but some other proteases may also involve in this activation mechanism.
Açıklama
Anahtar Kelimeler
Growth-Factor-Beta, Tgf-Beta, Transforming Growth-Factor-Beta-1, Extracellular-Matrix, Binding-Proteins, Cancer, Thrombospondin-1, Cells, Urokinase, Mechanism
Kaynak
Cancer Investigation
WoS Q Değeri
Q3
Scopus Q Değeri
Q2
Cilt
26
Sayı
1
