Salivary function in patients with chronic renal failure undergoing hemodialysis

Basit Öğe Kaydı
dc.authoridCermik, Tevfik Fikret/0000-0001-7622-7277
dc.authorwosidCermik, Tevfik Fikret/A-9694-2018
dc.contributor.authorKaya, M
dc.contributor.authorÇermik, TF
dc.contributor.authorÜstün, F
dc.contributor.authorSen, S
dc.contributor.authorBerkarda, S
dc.date.accessioned2024-06-12T10:56:31Z
dc.date.available2024-06-12T10:56:31Z
dc.date.issued2002
dc.departmentTrakya Üniversitesien_US
dc.description.abstractPurpose: The aim of this study was to evaluate the changes in salivary gland function in patients with chronic renal failure (CRF) undergoing hemodialysis. Methods: The group consisted of 23 patients with CRF (13 female, 10 males mean age: 40 +/- 13 yr) and 14 healthy control subjects (mean age: 40 +/- 13 yr). All underwent dynamic salivary gland scintigraphy with gustatory stimulation, After intravenous administration of Tc-99m pertechnetate, first. perfusion images at 2 seconds per frame were acquired for I minute, then dynamic images at 1 minute per frame were acquired for 45 minutes, At 30 minutes after injection, 10 ml lemon juice was given for 15 minutes as a gustatory stimulus. We obtained time-activity curves derived from regions of interest centered over the four major salivary glands. The following functional indices were calculated for each gland: the time of maximum radioactivity (T-max) for the prestimulated period, the time of minimum radioactivity (T-min), as an indicator of velocity of secretion after stimulation, and the Lem E-5% value as an indicator of the secretion function. Results: When the patients with CRF undergoing hemodialysis were compared to the controls, there were statistically significant differences in T-max, T-min and Lem E5% values for bilateral parotid glands, and Train values for bilateral submandibular glands (p < 0.05), there were no statistically significant differences in Tmax and Lem E5% values for bilateral submandibular glands. There were also significant differences in T-max and Lem E5% values for bilateral parotid glands between mild oral problems and severe oral problems in patients with CRF (undergoing hemodialysis). Conclusion: In this study, prolonged T-max and T-min values, and decreased Lem E5% values for parotid glands and prolonged T-min values for submandibular glands on salivary scintigraphy pointed out decreased parenchymatous and excretory function in patients with CRF undergoing hemodialysis.en_US
dc.identifier.doi10.1007/BF02993714
dc.identifier.endpage120en_US
dc.identifier.issn0914-7187
dc.identifier.issue2en_US
dc.identifier.pmid12043905en_US
dc.identifier.scopus2-s2.0-0036001348en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage117en_US
dc.identifier.urihttps://doi.org/10.1007/BF02993714
dc.identifier.urihttps://hdl.handle.net/20.500.14551/19816
dc.identifier.volume16en_US
dc.identifier.wosWOS:000175567000005en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherJapanese Society Nuclear Medicineen_US
dc.relation.ispartofAnnals Of Nuclear Medicineen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectChronic Renal Failureen_US
dc.subjectSalivary Functionen_US
dc.subjectScintigraphyen_US
dc.subjectGland Scintigraphyen_US
dc.subjectSjogrens-Syndromeen_US
dc.subjectStageen_US
dc.subjectDiseaseen_US
dc.titleSalivary function in patients with chronic renal failure undergoing hemodialysisen_US
dc.typeArticleen_US

Dosyalar

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
PubMed İndeksli Yayınlar Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu