Salivary function in patients with chronic renal failure undergoing hemodialysis
dc.authorid | Cermik, Tevfik Fikret/0000-0001-7622-7277 | |
dc.authorwosid | Cermik, Tevfik Fikret/A-9694-2018 | |
dc.contributor.author | Kaya, M | |
dc.contributor.author | Çermik, TF | |
dc.contributor.author | Üstün, F | |
dc.contributor.author | Sen, S | |
dc.contributor.author | Berkarda, S | |
dc.date.accessioned | 2024-06-12T10:56:31Z | |
dc.date.available | 2024-06-12T10:56:31Z | |
dc.date.issued | 2002 | |
dc.department | Trakya Üniversitesi | en_US |
dc.description.abstract | Purpose: The aim of this study was to evaluate the changes in salivary gland function in patients with chronic renal failure (CRF) undergoing hemodialysis. Methods: The group consisted of 23 patients with CRF (13 female, 10 males mean age: 40 +/- 13 yr) and 14 healthy control subjects (mean age: 40 +/- 13 yr). All underwent dynamic salivary gland scintigraphy with gustatory stimulation, After intravenous administration of Tc-99m pertechnetate, first. perfusion images at 2 seconds per frame were acquired for I minute, then dynamic images at 1 minute per frame were acquired for 45 minutes, At 30 minutes after injection, 10 ml lemon juice was given for 15 minutes as a gustatory stimulus. We obtained time-activity curves derived from regions of interest centered over the four major salivary glands. The following functional indices were calculated for each gland: the time of maximum radioactivity (T-max) for the prestimulated period, the time of minimum radioactivity (T-min), as an indicator of velocity of secretion after stimulation, and the Lem E-5% value as an indicator of the secretion function. Results: When the patients with CRF undergoing hemodialysis were compared to the controls, there were statistically significant differences in T-max, T-min and Lem E5% values for bilateral parotid glands, and Train values for bilateral submandibular glands (p < 0.05), there were no statistically significant differences in Tmax and Lem E5% values for bilateral submandibular glands. There were also significant differences in T-max and Lem E5% values for bilateral parotid glands between mild oral problems and severe oral problems in patients with CRF (undergoing hemodialysis). Conclusion: In this study, prolonged T-max and T-min values, and decreased Lem E5% values for parotid glands and prolonged T-min values for submandibular glands on salivary scintigraphy pointed out decreased parenchymatous and excretory function in patients with CRF undergoing hemodialysis. | en_US |
dc.identifier.doi | 10.1007/BF02993714 | |
dc.identifier.endpage | 120 | en_US |
dc.identifier.issn | 0914-7187 | |
dc.identifier.issue | 2 | en_US |
dc.identifier.pmid | 12043905 | en_US |
dc.identifier.scopus | 2-s2.0-0036001348 | en_US |
dc.identifier.scopusquality | Q2 | en_US |
dc.identifier.startpage | 117 | en_US |
dc.identifier.uri | https://doi.org/10.1007/BF02993714 | |
dc.identifier.uri | https://hdl.handle.net/20.500.14551/19816 | |
dc.identifier.volume | 16 | en_US |
dc.identifier.wos | WOS:000175567000005 | en_US |
dc.identifier.wosquality | Q4 | en_US |
dc.indekslendigikaynak | Web of Science | en_US |
dc.indekslendigikaynak | Scopus | en_US |
dc.indekslendigikaynak | PubMed | en_US |
dc.language.iso | en | en_US |
dc.publisher | Japanese Society Nuclear Medicine | en_US |
dc.relation.ispartof | Annals Of Nuclear Medicine | en_US |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |
dc.rights | info:eu-repo/semantics/closedAccess | en_US |
dc.subject | Chronic Renal Failure | en_US |
dc.subject | Salivary Function | en_US |
dc.subject | Scintigraphy | en_US |
dc.subject | Gland Scintigraphy | en_US |
dc.subject | Sjogrens-Syndrome | en_US |
dc.subject | Stage | en_US |
dc.subject | Disease | en_US |
dc.title | Salivary function in patients with chronic renal failure undergoing hemodialysis | en_US |
dc.type | Article | en_US |