Bone marrow involvement in sarcoidosis: an analysis of 50 bone marrow samples

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dc.contributor.authorYanardag, H
dc.contributor.authorPamuk, GE
dc.contributor.authorKarayel, T
dc.contributor.authorDemirci, S
dc.date.accessioned2024-06-12T11:13:53Z
dc.date.available2024-06-12T11:13:53Z
dc.date.issued2002
dc.departmentTrakya Üniversitesien_US
dc.description.abstractThe incidence of bone marrow involvement in sarcoidosis patients and changes in their peripheral blood parameters have been investigated. Out of 92 patients diagnosed with sarcoidosis at our center between 1994 and 2002, 50 (54.3%) gave consent for a bone marrow biopsy and were included into our study. The clinical features, peripheral blood parameters and bone marrow biopsy findings of the patients were analysed. Of these 50 patients, 39 were females and 11 were males (median age 37 years, range 16-62). Anemia was detected in 11 (22%) cases, and both anemia and leucopenia in 3 (6%). In 10% (5 patients; 3 males, 2 females) of the patients, bone marrow biopsy revealed noncaseified granulomas. Sarcoidosis patients with bone marrow involvement had higher incidences of extrapulmonary involvement, leucopenia-lymphopenia and anemia than those without involvement (P values were, 0.05, 0.001 and 0.06, respectively). Of the 11 patients with anemia, 3 had involvement of the bone marrow by sarcoidosis and 7 had iron deficiency anemia. As a result, bone marrow involvement should be considered in sarcoidosis patients with anemia, leucopenia-lymphopenia, and also extrapulmonary involvement.en_US
dc.identifier.endpage425en_US
dc.identifier.issn0017-6559
dc.identifier.issue4en_US
dc.identifier.pmid12803116en_US
dc.identifier.scopus2-s2.0-0037981541en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage419en_US
dc.identifier.urihttps://hdl.handle.net/20.500.14551/23713
dc.identifier.volume32en_US
dc.identifier.wosWOS:000183326800012en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherVsp Bven_US
dc.relation.ispartofHaematologiaen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectSarcoidosisen_US
dc.subjectBone Marrow Involvementen_US
dc.subjectAnemiaen_US
dc.subjectLeucopeniaen_US
dc.subjectLymphopeniaen_US
dc.subjectExtrapulmonary Involvementen_US
dc.titleBone marrow involvement in sarcoidosis: an analysis of 50 bone marrow samplesen_US
dc.typeArticleen_US

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