Pericardial SCUBE1 levels may help predict postoperative results in patients operated on for coronary artery bypass graft surgery

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dc.authoridYuksel, Volkan/0000-0001-9518-2588
dc.authoridOzkara, Taha/0000-0002-9245-5584
dc.contributor.authorOzkara, Taha
dc.contributor.authorYuksel, Volkan
dc.contributor.authorGuclu, Orkut
dc.contributor.authorHuseyin, Serhat
dc.contributor.authorOzgun, Eray
dc.contributor.authorTuran, Fatma Nesrin
dc.contributor.authorCanbaz, Suat
dc.date.accessioned2024-06-12T10:58:35Z
dc.date.available2024-06-12T10:58:35Z
dc.date.issued2021
dc.departmentTrakya Üniversitesien_US
dc.description15th Turkish-Society-of-Thoracic-and-Cardiovascular-Surgery Congress -- OCT 26-29, 2018 -- Antalya, TURKEYen_US
dc.description.abstractIntroduction: Signal peptide-CUB epidermal growth factor like domain-containing protein (SCUBE1) is a newly described, secretable and measurable cellular surface protein associated with atherosclerotic lesions in humans, which may be involved in hypertension and cardiovascular pathologies. We aimed to detect normal SCUBE1 levels in pericardial fluid and investigate the effects of SCUBE1 values on postoperative outcomes after coronary artery bypass surgery. Methods: Between February 2016 and March 2017, 184 consecutive patients were included in the study. Group 1 consisted of patients with unstable angina pectoris, group 2 of patients with non-ST-elevation myocardial infarction, group 3 of patients with ST-elevation myocardial infarction, and group 4 consisted of patients operated on due to non -coronary reasons. Pericardial fluid and arterial blood SCUBE1 values, demographic variables and postoperative results were noted and compared. Results: Normal SCUBE1 level in pericardial fluid was 0.049 +/- 0.061 ng/ml. Arterial SCUBE1 levels of smokers were higher. Pericardial SCUBE1 levels were higher in patients requiring postoperative intra-aortic balloon pump support and patients needing peri-operative temporary cardiac pacing. High pericardial SCUBE1 values did not correlate with postoperative stroke, prolonged intensive care unit stay and mortality. Conclusion: High levels of pericardial SCUBE1 may help us predict the need for postoperative intra-aortic balloon pump support and the need for temporary cardiac pacing, however they were not helpful in predicting prolonged intensive care unit stay and early postoperative mortality.en_US
dc.description.sponsorshipTurkish Soc Thorac & Cardiovascular Surgen_US
dc.identifier.doi10.5830/CVJA-2021-020
dc.identifier.endpage247en_US
dc.identifier.issn1995-1892
dc.identifier.issn1680-0745
dc.identifier.issue5en_US
dc.identifier.pmid34292290en_US
dc.identifier.scopus2-s2.0-85121157622en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage243en_US
dc.identifier.urihttps://doi.org/10.5830/CVJA-2021-020
dc.identifier.urihttps://hdl.handle.net/20.500.14551/20118
dc.identifier.volume32en_US
dc.identifier.wosWOS:000798219200003en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherClinics Cardive Publ Pty Ltden_US
dc.relation.ispartofCardiovascular Journal Of Africaen_US
dc.relation.publicationcategoryKonferans Öğesi - Uluslararası - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectCoronary Artery Bypass Surgeryen_US
dc.subjectSCUBE 1en_US
dc.subjectPostoperative Complicationen_US
dc.subjectDomain-Containing Protein-1en_US
dc.subjectDiagnostic-Valueen_US
dc.subjectEuroscore Iien_US
dc.subjectBiomarkeren_US
dc.subjectTermen_US
dc.titlePericardial SCUBE1 levels may help predict postoperative results in patients operated on for coronary artery bypass graft surgeryen_US
dc.typeConference Objecten_US

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