Anthropometric and Biochemical Assessment of Nutritional Status in Pediatric Cancer Patients

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dc.authorideren, tuba/0000-0001-5471-0663;
dc.authorwosideren, tuba/JTU-4270-2023
dc.authorwosidSari, Neriman/N-1461-2018
dc.contributor.authorIlhan, Inci Erguhan
dc.contributor.authorSari, Neriman
dc.contributor.authorYesil, Sule
dc.contributor.authorEren, Tuba
dc.contributor.authorTacyildiz, Nurdan
dc.date.accessioned2024-06-12T10:55:34Z
dc.date.available2024-06-12T10:55:34Z
dc.date.issued2015
dc.departmentTrakya Üniversitesien_US
dc.description.abstractChildren are at greater risk for malnutrition due to increased needs of nutrients to obtain appropriate growth, and they exhibit elevated substrate needs due to cancer and its treatment. This study aimed to report anthropometric and biochemical evaluation of nutritional status in children with cancer at initial presentation and during treatment. A prospective, controlled study was performed in the pediatric oncology department of a tertiary care center. Control group consisted of the siblings of patients. Weight, height, body mass index, triceps skinfold thickness, and serum levels of total protein, albumin, prealbumin, serum lipids, trace minerals, C-reactive protein (CRP), and vitamins were compared in patients and controls at initial presentation and at 6th month after the onset of treatment. According to weight for height, the frequency of malnutrition was 16% at initial presentation and 22% at 6th month. Triceps skinfold thickness was significantly thinner in patients than controls at both measurements. Patients had lower levels of prealbumin, albumin, iron, folate, zinc, and vitamin C and higher levels of ferritin, vitamin B-12, and copper. Serum CRP levels were significantly higher in cancer patients at initial presentation and seemed to be correlated with copper levels. Compared with other patients, malnourished patients had significantly higher levels of vitamin B-12 at 6th month. Results of the current study demonstrate that trace minerals, vitamins, and anthropometric measures may yield important clues for nutritional status and disease activity in pediatric oncology patients. However, validation and updating these potential markers warrant further trials on larger series.en_US
dc.description.sponsorshipTurkish Pediatric Oncology Group Scientific Research Projects Programen_US
dc.description.sponsorshipThis study was funded by Turkish Pediatric Oncology Group Scientific Research Projects Program (2009).en_US
dc.identifier.doi10.3109/08880018.2015.1046096
dc.identifier.endpage422en_US
dc.identifier.issn0888-0018
dc.identifier.issn1521-0669
dc.identifier.issue6en_US
dc.identifier.pmid26237587en_US
dc.identifier.scopus2-s2.0-84942823515en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage415en_US
dc.identifier.urihttps://doi.org/10.3109/08880018.2015.1046096
dc.identifier.urihttps://hdl.handle.net/20.500.14551/19474
dc.identifier.volume32en_US
dc.identifier.wosWOS:000369740000007en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherTaylor & Francis Incen_US
dc.relation.ispartofPediatric Hematology And Oncologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectCanceren_US
dc.subjectChildrenen_US
dc.subjectMalnutritionen_US
dc.subjectTrace Mineralsen_US
dc.subjectVitaminsen_US
dc.subjectWeighten_US
dc.subjectChildrenen_US
dc.subjectMalnutritionen_US
dc.subjectTetrathiomolybdateen_US
dc.subjectPercentilesen_US
dc.subjectDiagnosisen_US
dc.subjectTherapyen_US
dc.subjectWeighten_US
dc.subjectHeighten_US
dc.titleAnthropometric and Biochemical Assessment of Nutritional Status in Pediatric Cancer Patientsen_US
dc.typeArticleen_US

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