Clinical characteristics of haematological malignancy patients diagnosed with leukaemia cutis: Experience of a single centre

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dc.authorwosidHarmandar, Ferda/AAD-3862-2019
dc.contributor.authorPamuk, Gulsum Emel
dc.contributor.authorAk, Recep
dc.contributor.authorTasci, Murat
dc.contributor.authorHarmandar, Ferda
dc.contributor.authorDemir, Muzaffer
dc.contributor.authorArican, Ozer
dc.date.accessioned2024-06-12T11:02:53Z
dc.date.available2024-06-12T11:02:53Z
dc.date.issued2015
dc.departmentTrakya Üniversitesien_US
dc.description.abstractBackground/ObjectivesWe evaluated the clinical characteristics of patients with haematological malignancies at our centre who were diagnosed with leukaemia cutis (LC). In addition, we describe the spectrum of other skin lesions, including, secondary skin malignancies and nonspecific benign skin lesions in haematological malignancy patients. MethodsWe defined 58 skin lesions that developed in 54 inpatients hospitalised in the Department of Haematology, Trakya University Medical Faculty, Turkey. All skin lesions that developed in inpatients between 2006 and 2012 had been evaluated by a dermatologist. The patients' clinical features, skin biopsy results and therapies were obtained from hospital files. The diagnosis of LC was based on clinical features and histopathological examinations of the skin biopsy. ResultsThere were 11 patients with LC. Six (54.5%) had acute myeloblastic leukaemia. In nine patients (82%), LC was present at the initial presentation. Secondary skin malignancy was detected in 11 patients (five basal cell carcinoma, four Kaposi's sarcoma, one squamous cell carcinoma, one malignant melanoma); and malignancy was present in two patients (18%) at the initial presentation. Nonspecific benign skin lesions, the most frequent of which were drug eruptions, were determined in 32 of our patients. LC had a significantly higher likelihood of being present at initial presentation than other skin lesions (P<0.01). The median survival in LC patients was quite short (4.5 months). ConclusionsLC was usually diagnosed at the initial presentation of the patient or during the early course of the disease. Having LC was a poor prognostic factor.en_US
dc.identifier.doi10.1111/ajd.12193
dc.identifier.endpage119en_US
dc.identifier.issn0004-8380
dc.identifier.issn1440-0960
dc.identifier.issue2en_US
dc.identifier.pmid25367408en_US
dc.identifier.scopus2-s2.0-84928109073en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage116en_US
dc.identifier.urihttps://doi.org/10.1111/ajd.12193
dc.identifier.urihttps://hdl.handle.net/20.500.14551/21455
dc.identifier.volume56en_US
dc.identifier.wosWOS:000353337700013en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherWileyen_US
dc.relation.ispartofAustralasian Journal Of Dermatologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectHaematological Malignancyen_US
dc.subjectLeukaemia Cutisen_US
dc.subjectNonspecific Benign Skin Lesionen_US
dc.subjectSecondary Skin Malignancyen_US
dc.subjectAcute Myeloid-Leukemiaen_US
dc.subjectCanceren_US
dc.titleClinical characteristics of haematological malignancy patients diagnosed with leukaemia cutis: Experience of a single centreen_US
dc.typeArticleen_US

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