99mTc-HMPAO single photon emission computed tomography (SPECT) in both asphyxiated and epileptic children with or without status epilepticus

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dc.authoridCermik, Tevfik Fikret/0000-0001-7622-7277
dc.authoridTuran, Cemal/0000-0001-9584-0261
dc.authorwosidCermik, Tevfik Fikret/A-9694-2018
dc.authorwosidTuran, Cemal/Q-7638-2019
dc.contributor.authorÖner, N
dc.contributor.authorCermik, TF
dc.contributor.authorAlpay, M
dc.contributor.authorTuran, Ç
dc.contributor.authorAladag, N
dc.contributor.authorKarasalihoglu, S
dc.date.accessioned2024-06-12T11:22:24Z
dc.date.available2024-06-12T11:22:24Z
dc.date.issued2005
dc.departmentTrakya Üniversitesien_US
dc.description.abstractIn this study, technetium 99m hexamethylpropyleneamine oxime (Tc-99m-HMPAO) single photon emission computed tomography (SPECT) was performed on 18 asphyxiated and epileptic children who also had a status epilepticus episode, and the results were compared with those for 21 children without a status epilepticus episode. All patients underwent a detailed neurologic history, interictal electroencephalography, computed tomography, and/or magnetic resonance imaging. Visual evaluation of the SPECT study showed that 16 patients of group 1 had 56 hypoperfused regions in cerebral blood flow. However, in group 2, visual evaluation showed only six detectable hypoperfusion areas in five patients. When an asymmetric index value of 3 was considered as a cutoff point, 82 regions in group 1 and 57 regions in group 2 were above this value after the quantitative SPECT evaluation. The mean number of pathologic brain regions was found to be higher in group 1 (5.1 +/- 4.3) than in group 2 (2.7 +/- 2.4) (P = .014). The localization of hypoperfused regions that were observed in temporal and frontal regions was generally similar in both groups. In conclusion, the functional activities of the brain vary in both asphyetic and epileptic children, with and without status epilepticus. These children might be candidates for refractory convulsive disease, and interictal SPECT can be a reliable method for the detection of brain lesions in these patients.en_US
dc.identifier.doi10.1177/08830738050200070301
dc.identifier.endpage565en_US
dc.identifier.issn0883-0738
dc.identifier.issn1708-8283
dc.identifier.issue7en_US
dc.identifier.pmid16159519en_US
dc.identifier.scopus2-s2.0-24344487992en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage560en_US
dc.identifier.urihttps://doi.org/10.1177/08830738050200070301
dc.identifier.urihttps://hdl.handle.net/20.500.14551/25892
dc.identifier.volume20en_US
dc.identifier.wosWOS:000231048600003en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherSage Publications Incen_US
dc.relation.ispartofJournal Of Child Neurologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subject[No Keywords]en_US
dc.title99mTc-HMPAO single photon emission computed tomography (SPECT) in both asphyxiated and epileptic children with or without status epilepticusen_US
dc.typeArticleen_US

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