Long term follow-up results of 139 Turkish children and adolescents with rheumatic heart disease

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dc.authorideker, rukiye/0000-0002-3740-6552
dc.authorwosidnişli, kemal/AAT-6434-2020
dc.authorwosidÖmeroğlu, Rukiye Nurten/AAT-7658-2020
dc.contributor.authorYavuz, Taner
dc.contributor.authorNisli, Kemal
dc.contributor.authorOner, Naci
dc.contributor.authorDindar, Aygun
dc.contributor.authorAydogan, Umrah
dc.contributor.authorOmeroglu, Rukiye Eker
dc.contributor.authorErtugrul, Turkan
dc.date.accessioned2024-06-12T11:13:39Z
dc.date.available2024-06-12T11:13:39Z
dc.date.issued2008
dc.departmentTrakya Üniversitesien_US
dc.description.abstractWe aimed to evaluate the predictors of the severity of chronic rheumatic valvar disease. The long term follow-up records of 139 patients with chronic rheumatic carditis were reviewed. Children were followed-up on an outpatient basis for a period ranging from 1-16 years (5.0 +/- 3.7 years). Mitral regurgitation either isolated (51%, n=71) or combined with aortic regurgitation (AR) (49%, n = 68) was observed in all cases of the initial attack of rheumatic carditis. AR at initial attack of the rheumatic carditis was found to be affected by gender (AR was more associated with males, p = 0.032), combined mitral and aortic regurgitation (CMAR), and presence of MR at initial attack (p = 0.000 and p = 0.012, respectively) with univariate analysis. The effect of CMAR on AR at initial attack was also significant by multivariate analysis (p = 0.000). CMAR, MR, and AR at initial attack had significant effects on CMAR at final evaluation (p = 0.000, p = 0.020, and p = 0.000, respectively) in univariate analysis. Multivariate analysis revealed the significant effects of CMAR and MR at initial attack on CMAR at final evaluation (p = 0.000 and p = 0.005, respectively). Univariate analysis showed that MR and AR at initial attack, and CMAR at final evaluation, had significant effects on MR at final evaluation (p = 0.000, p = 0.029, and p = 0.000, respectively). MR at initial attack and CMAR at final evaluation had significant effects on MR at final evaluation with multivariate analysis (p = 0.001 and p = 0.003, respectively). AR at final evaluation was affected by CMAR and AR at initial attack (p = 0.000 and p = 0.000, respectively), and CMAR and MR at final evaluation (p = 0.000 and p = 0.000, respectively) with both univariate and multivariate analysis. Mitral valve prolapsus was more common in patients with a longer duration (37.5%, 6 out of 16) than those with a shorter duration (11%, 14 out of 123) and the difference was significant (p = 0.020). In conclusion, the initial severity of valve involvement and the presence of CMAR at initial attack were found to be the best predictors for the severity of chronic rheumatic valvar disease in this study.en_US
dc.identifier.doi10.1007/s00431-008-0799-6
dc.identifier.endpage1326en_US
dc.identifier.issn0340-6199
dc.identifier.issue11en_US
dc.identifier.pmid18668262en_US
dc.identifier.scopus2-s2.0-51849116288en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage1321en_US
dc.identifier.urihttps://doi.org/10.1007/s00431-008-0799-6
dc.identifier.urihttps://hdl.handle.net/20.500.14551/23634
dc.identifier.volume167en_US
dc.identifier.wosWOS:000259247300014en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherSpringeren_US
dc.relation.ispartofEuropean Journal Of Pediatricsen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectRheumatic Heart Diseaseen_US
dc.subjectRheumatic Feveren_US
dc.subjectPredictoren_US
dc.subjectMitral Regurgitationen_US
dc.subjectAortic Regurgitationen_US
dc.subjectMitral Regurgitationen_US
dc.subjectEchocardiographic Evaluationen_US
dc.subjectValvar Diseaseen_US
dc.subjectFeveren_US
dc.subjectCarditisen_US
dc.subjectAnkaraen_US
dc.subjectTurkeyen_US
dc.titleLong term follow-up results of 139 Turkish children and adolescents with rheumatic heart diseaseen_US
dc.typeArticleen_US

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