Distal sensorimotor polyneuropathy affects skeletal muscle perfusion and metabolism by Tc-99m sestarnibi leg scintigraphy in patients with type 2 diabetes

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dc.authoridDURMUS ALTUN, GULAY/0000-0002-1822-9386
dc.authoridAltun, Armagan/0000-0002-3233-8263
dc.authorwosidDURMUS ALTUN, GULAY/S-6586-2016
dc.authorwosidAltun, Armagan/ABB-5844-2020
dc.contributor.authorUgur-Altun, B
dc.contributor.authorDurmus-Altun, G
dc.contributor.authorUstun, F
dc.contributor.authorTurgut, N
dc.contributor.authorAltun, A
dc.contributor.authorTugrul, A
dc.date.accessioned2024-06-12T11:16:51Z
dc.date.available2024-06-12T11:16:51Z
dc.date.issued2005
dc.departmentTrakya Üniversitesien_US
dc.description.abstractWe evaluated the effects of distal symmetric sensorimotor polyneuropathy (DSP) on skeletal muscle perfusion and metabolism in patients with type 2 diabetes. Twenty-three patients with type 2 diabetes under-went electrophysiological and Tc-99m sesta-mibi leg scintigraphic studies. The study patients were divided into 2 groups: group I (n = 14) with DSP and group 11 (n = 9) without DSP. We found decreased Tc-99m sestamibi uptake ratios (UR) of both legs in patients with DSP (right UR 7.98 +/- 6.85, left UR 7.78 +/- 7.01 vs. right UR 8.91 +/- 7.98, left UR 8.67 +/- 8.23, respectively) than without DSP, although it did not reach statistical significance. The regression equation of right UR was (Tc-99m sestarnibi UR = [1.927 X velocity of tibial nerve] - [0.942 X amplitude of sural nerve] - 81.94). In conclusion, electrophysiological variables of tibial motor and sural sensory nerves predict Tc-99m sestarnibi UR at leg scintigraphy in patients with type 2 diabetes. Additionally, decreased Tc-99m sestarnibi UR in patients with type 2 diabetes with DSP was found.en_US
dc.identifier.doi10.1097/01.ten.0000164211.52984.90
dc.identifier.endpage149en_US
dc.identifier.issn1051-2144
dc.identifier.issn1539-9192
dc.identifier.issue3en_US
dc.identifier.scopus2-s2.0-18844434414en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage146en_US
dc.identifier.urihttps://doi.org/10.1097/01.ten.0000164211.52984.90
dc.identifier.urihttps://hdl.handle.net/20.500.14551/24479
dc.identifier.volume15en_US
dc.identifier.wosWOS:000229307700005en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherLippincott Williams & Wilkinsen_US
dc.relation.ispartofEndocrinologisten_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectType 2 Diabetes Mellitusen_US
dc.subjectNeuropathyen_US
dc.subjectLeg Scintigraphyen_US
dc.subjectTc-99m Sestamibien_US
dc.subjectUptake Ratioen_US
dc.subjectNeuropathyen_US
dc.subjectReflexen_US
dc.subjectFooten_US
dc.titleDistal sensorimotor polyneuropathy affects skeletal muscle perfusion and metabolism by Tc-99m sestarnibi leg scintigraphy in patients with type 2 diabetesen_US
dc.typeArticleen_US

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