Importance of pulmonary artery perfusion in cardiac surgery

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dc.authoridYALCIN, OMER TARIK/0000-0001-5626-1881
dc.authorwosidYALCIN, OMER TARIK/B-4744-2018
dc.contributor.authorEge, T
dc.contributor.authorHuseyin, G
dc.contributor.authorYalcin, O
dc.contributor.authorUs, MH
dc.contributor.authorArar, C
dc.contributor.authorDuran, E
dc.date.accessioned2024-06-12T11:13:07Z
dc.date.available2024-06-12T11:13:07Z
dc.date.issued2004
dc.departmentTrakya Üniversitesien_US
dc.description.abstractObjective: To investigate the importance of pulmonary artery perfusion in cardiac surgery. Design: Prospective randomized study. Setting: University hospital. Participants: Patients undergoing cardiac surgery. Interventions: Patients in whom the cross-clamp was applied only to the aorta were defined as group 1 (n = 11) and patients in whom the cross-clamp was applied to both the aorta and pulmonary artery were defined as group 2 (n = 11). Measurement and Results: Tissue samples obtained from the lower lobe of the left lung before CPB, 20 minutes after cross-clamping, and 20 minutes after declamping were examined under light and electron microscopes. Electron microscopic examination revealed changes in the blood-air barrier, epithelia[ cells, pneumocytes, and basal membrane were more prominent in group 2. Changes in the leukocyte, neutrophil, and lymphocyte counts of blood samples obtained from the right atrium and right superior pulmonary vein before CPB and 5, 30, 60, and 90 minutes after the removal of clamp were also investigated. The transpulmonary difference was statistically significant at 5 and 30 minutes after declamping in group 1. In group 2, transpulmonary differences continued to be significant at 5, 30, 60, and 90 minutes after declamping. There was no difference between groups in terms of PaO2/F1O2 ratio before CPB (group 1: 342.0 +/- 80.0 mmHg, group 2: 349.0 +/- 67.0 mmHg); however, a statistically significant difference was found between the groups 2 hours after declamping (group 1: 418.0 +/- 87.0 mmHg and group 2: 290.0 +/- 110.0 mmHg; p = 0.007). Conclusion: Pulmonary artery perfusion was found to be important in cardiac surgery. (C) 2004 Elsevier Inc. All rights reserved.en_US
dc.identifier.doi10.1053/j.jvca.2004.01.022
dc.identifier.endpage174en_US
dc.identifier.issn1053-0770
dc.identifier.issn1532-8422
dc.identifier.issue2en_US
dc.identifier.pmid15073706en_US
dc.identifier.scopus2-s2.0-1942454807en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage166en_US
dc.identifier.urihttps://doi.org/10.1053/j.jvca.2004.01.022
dc.identifier.urihttps://hdl.handle.net/20.500.14551/23428
dc.identifier.volume18en_US
dc.identifier.wosWOS:000220941500010en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherW B Saunders Co-Elsevier Incen_US
dc.relation.ispartofJournal Of Cardiothoracic And Vascular Anesthesiaen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectPulmonary Artery Perfusionen_US
dc.subjectBlood-Air Barrieren_US
dc.subjectElectron Microscopyen_US
dc.subjectCardiopulmonary Bypassen_US
dc.subjectLung Injuryen_US
dc.subjectInflammatory Responseen_US
dc.subjectReperfusionen_US
dc.subjectDysfunctionen_US
dc.subjectIschemiaen_US
dc.titleImportance of pulmonary artery perfusion in cardiac surgeryen_US
dc.typeArticleen_US

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