Plasma copeptin levels in the patients with gastrointestinal bleeding

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dc.authoridOzkan, Seda/0000-0003-1835-8820
dc.authoridSALT, OMER/0000-0002-5557-6627
dc.authorwosidşen, ahmet/S-1096-2017
dc.authorwosidOzkan, Seda/AAE-8598-2019
dc.contributor.authorSalt, Omer
dc.contributor.authorDurukan, Polat
dc.contributor.authorOzkan, S.
dc.contributor.authorSaraymen, R.
dc.contributor.authorSen, A.
dc.contributor.authorYurci, M. A.
dc.date.accessioned2024-06-12T10:58:29Z
dc.date.available2024-06-12T10:58:29Z
dc.date.issued2017
dc.departmentTrakya Üniversitesien_US
dc.description.abstractIntroduction: Gastrointestinal bleeding is a significant cause of morbidity andmortality worldwide. In addition, it constitutes an important part of health expenditures. In this study, we aimed to determine whether there is a relationship between plasma copeptin levels and the etiology, location and severity of gastrointestinal bleeding. Materials and methods: This study was performed prospectively in 104 consecutive patients who were admitted to anemergency department with complaints of bloody vomiting or bloody or black stool. To evaluate the level of biochemical parameters such as Full Blood Count (FBC), serumbiochemistry, bleeding parameters and copeptin, blood samples were obtained at admission. For the copeptin levels, 2 more blood samples were obtained at the 12th and 24th hours after admission. The values obtained were compared using statistical methods. Results: In terms of the etiology of bleeding, the copeptin levels in the patients with peptic ulcer were higher than the levels in patients with other gastrointestinal bleeding. However, the difference was not statistically significant. There were no significant differences among all groups' 0th, 12th and 24th hour levels of copeptin. Discussion: We conclude that copeptin cannot be effectively used as a biochemical parameter in an emergency department to determine the etiology and location of gastrointestinal bleeding. It can, however, be used to make decisions on endoscopy and the hospitalization of patients with suspected gastrointestinal bleeding. (C) 2017 Elsevier Inc. All rights reserved.en_US
dc.identifier.doi10.1016/j.ajem.2017.04.033
dc.identifier.endpage1443en_US
dc.identifier.issn0735-6757
dc.identifier.issn1532-8171
dc.identifier.issue10en_US
dc.identifier.pmid28431872en_US
dc.identifier.scopus2-s2.0-85018316347en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage1440en_US
dc.identifier.urihttps://doi.org/10.1016/j.ajem.2017.04.033
dc.identifier.urihttps://hdl.handle.net/20.500.14551/20088
dc.identifier.volume35en_US
dc.identifier.wosWOS:000415183400011en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherW B Saunders Co-Elsevier Incen_US
dc.relation.ispartofAmerican Journal Of Emergency Medicineen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectCopeptinen_US
dc.subjectEmergency Departmenten_US
dc.subjectGastrointestinal Bleedingen_US
dc.subjectNational Asge Surveyen_US
dc.subjectArginine-Vasopressinen_US
dc.titlePlasma copeptin levels in the patients with gastrointestinal bleedingen_US
dc.typeArticleen_US

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