Changes in intra-ocular pressure, ocular pulse amplitude and choroidal thickness after trabeculectomy

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dc.authoridAltan, Cigdem Ayse/0000-0002-0908-6619
dc.authoridGarip, Ruveyde/0000-0003-2235-9017
dc.authorwosidAltan, Cigdem Ayse/AAL-2041-2020
dc.contributor.authorCicek, Ugur
dc.contributor.authorGarip, Ruveyde
dc.contributor.authorSolmaz, Banu
dc.contributor.authorAltan, Cigdem
dc.date.accessioned2024-06-12T10:56:22Z
dc.date.available2024-06-12T10:56:22Z
dc.date.issued2023
dc.departmentTrakya Üniversitesien_US
dc.description.abstractBackground The aim of this study was to investigate the IOP, ocular pulse amplitude (OPA) and choroidal thickness (CT) changes after trabeculectomy and to determine whether trabeculectomy has an effect on ocular blood flow. Methods This retrospective, comparative case series was conducted with 33 eyes of 33 patients who underwent trabeculectomy due to uncontrolled glaucoma. The fellow eyes of 20 patients who were followed up with medical therapy were included as a control group. IOP and OPA were evaluated using a dynamic contour tonometer. Subfoveal choroidal thickness (SFCT) was obtained with enhanced depth imaging (EDI) mode of Spectralis-OCT. Results The mean IOP was 21.6 +/- 6.3 mmHg at baseline and 13.8 +/- 0.9 mmHg after trabeculectomy (p < 0.001), and the mean OPA was 4.1 +/- 1.5 at baseline and 2.6 +/- 1.6 mmHg after trabeculectomy (p < 0.001). The mean SFCT was 292.2 +/- 63.2 mu m at baseline and 303.8 +/- 70.4 mu m after trabeculectomy (p = 0.024). The change in OPA was strongly positively correlated with the change in IOP (r = 0.597, p < 0.001) and SFCT change was positively correlated with OPA change (r = 0.34, p = 0.05). There was no difference between the two groups in terms of IOP, OPA and SFCT values measured after trabeculectomy (respectively, p = 0.264, p = 0.627 and p = 0.949). Conclusion The large IOP decrease following trabeculectomy causes a decrease in OPA and choroidal thickening. On the other hand, trabeculectomy has no effect on OPA change.en_US
dc.identifier.doi10.1080/08164622.2021.2003690
dc.identifier.endpage40en_US
dc.identifier.issn0816-4622
dc.identifier.issn1444-0938
dc.identifier.issue1en_US
dc.identifier.pmid36628598en_US
dc.identifier.scopus2-s2.0-85121349881en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage36en_US
dc.identifier.urihttps://doi.org/10.1080/08164622.2021.2003690
dc.identifier.urihttps://hdl.handle.net/20.500.14551/19773
dc.identifier.volume106en_US
dc.identifier.wosWOS:000728703300001en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherTaylor & Francis Ltden_US
dc.relation.ispartofClinical And Experimental Optometryen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectChoroidal Thicknessen_US
dc.subjectIntra-Ocular Pressureen_US
dc.subjectOcular Pulse Amplitudeen_US
dc.subjectTrabeculectomyen_US
dc.subjectDynamic Contour Tonometryen_US
dc.subjectPerfusion-Pressureen_US
dc.subjectBlood-Flowen_US
dc.subjectGlaucomaen_US
dc.titleChanges in intra-ocular pressure, ocular pulse amplitude and choroidal thickness after trabeculectomyen_US
dc.typeArticleen_US

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