Investigation of the Factors Affecting Allograft Kidney Functions: Results of 10 Years

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dc.authoridSen, Sait/0000-0002-1100-6657
dc.authoridToz, Huseyin/0000-0002-2072-3586
dc.authoridGokalp, Cenk/0000-0003-3909-7973
dc.authorwosidGünay, Emrah/AAV-3418-2020
dc.authorwosidYILMAZ, MÜMTAZ/AAB-6851-2020
dc.authorwosidasci, gulay/B-9067-2018
dc.authorwosidGokalp, Cenk/AGW-1853-2022
dc.authorwosidSen, Sait/O-1489-2013
dc.contributor.authorGunay, Emrah
dc.contributor.authorCelebi, Tugba
dc.contributor.authorSen, Sait
dc.contributor.authorAsci, Gulay
dc.contributor.authorKumbaraci, Banu Sarsik
dc.contributor.authorGokalp, Cenk
dc.contributor.authorYilmaz, Mumtaz
dc.date.accessioned2024-06-12T11:19:47Z
dc.date.available2024-06-12T11:19:47Z
dc.date.issued2019
dc.departmentTrakya Üniversitesien_US
dc.description12th Congress of the Turkish-Transplantation-Centers-Coordination-Association (TTCCA) -- OCT 18-21, 2018 -- Trabzon, TURKEYen_US
dc.description.abstractIntroduction. Significant improvements in patient and graft survival and reductions in the frequency of acute rejection were obtained in the early period after renal transplantation, but this success was not sufficiently reflected in the long term. Allograft kidney losses in the long term remain a significant problem. In this study, we investigated the specific causes of graft losses in patients who had a good clinical course in the first year but developed graft loss in the long term. Methods. A total of 118 patients who underwent kidney transplantation in 2005 and 2006 in the Organ Transplantation Center of Ege University Medical Faculty Hospital were evaluated. The inclusion criteria were to be older than 18 years and have a serum creatinine value of <2 mg/dL at the 12th month after transplantation. Results. Sixty-one percent of the recipients were male, and the mean age at the time of transplantation was 34 +/- 11 years (18 to 61). We observed 29 graft losses during the mean follow-up period of 129 +/- 35 months (27 to 162). Three of the graft losses were death by functional graft. Of the 26 patients with graft loss, 16 had chronic rejection, and 8 had recurrent glomerulonephritis. The relationship between nonimmune causes and graft loss was not detected. Conclusions. In conclusion, nonimmune factors may not be as important as we think in relatively young and healthier recipients. Chronic rejection and recurrent glomerulonephritis are the main causes of long-term graft loss of patients with good graft function at the end of the first year. Improvement of long-term survival will be possible with the prevention and effective treatment of these 2 problems.en_US
dc.description.sponsorshipTurkish Transplantat Ctr Coordinat Assocen_US
dc.identifier.doi10.1016/j.transproceed.2019.02.014
dc.identifier.endpage1085en_US
dc.identifier.issn0041-1345
dc.identifier.issn1873-2623
dc.identifier.issue4en_US
dc.identifier.pmid31101175en_US
dc.identifier.scopus2-s2.0-85065575473en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage1082en_US
dc.identifier.urihttps://doi.org/10.1016/j.transproceed.2019.02.014
dc.identifier.urihttps://hdl.handle.net/20.500.14551/25346
dc.identifier.volume51en_US
dc.identifier.wosWOS:000500179300016en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherElsevier Science Incen_US
dc.relation.ispartofTransplantation Proceedingsen_US
dc.relation.publicationcategoryKonferans Öğesi - Uluslararası - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectRenal-Transplantationen_US
dc.subjectChronic Rejectionen_US
dc.subjectSurvivalen_US
dc.subjectRecurrenceen_US
dc.subjectDiseaseen_US
dc.subjectImpacten_US
dc.subjectRisksen_US
dc.titleInvestigation of the Factors Affecting Allograft Kidney Functions: Results of 10 Yearsen_US
dc.typeConference Objecten_US

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