Anemia and PET imaging

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dc.authoridSarikaya, Ismet/0000-0002-1087-580X
dc.authorwosidSarikaya, Ismet/G-7881-2015
dc.contributor.authorSarikaya, Ismet
dc.contributor.authorBaqer, Ali
dc.contributor.authorSarikaya, Ali
dc.date.accessioned2024-06-12T10:51:40Z
dc.date.available2024-06-12T10:51:40Z
dc.date.issued2021
dc.departmentTrakya Üniversitesien_US
dc.description.abstractAim Anemia is a blood disorder characterized by reduced Hemoglobin concentration and/or red blood cells numbers. Most common causes of anemia are iron deficiency anemia and anemia of chronic disease (anemia of chronic inflammation), but there is a long list of conditions which cause anemia. Bone marrow (BM), spleen, and liver are the main organs but various other tissues are also involved depending on the type of anemia. In this article, we aimed to review the role of PET imaging in anemia. Methods Normal BM, typical and atypical forms of hematopoiesis, pathogenesis of various forms of anemia, and PET findings in anemia with various radiotracers such as F-18-fluorodeoxyglucose, F-18-fluorothymidine, Fe-52 compounds and F-18-sodium fluoride were reviewed. Results In cases with anemia PET can help in determining the extent of BM expansion, distribution of BM, detecting proliferative activity of BM and BM islands in acellular BM on iliac biopsy, guiding BM biopsies, detecting typical or atypical extramedullary hematopoiesis, acute BM infarctions and various other complications such as osteomyelitis, cerebral infarction and infarction in various other tissues. Anemia-related PET findings can mimic tumor/metastases. Conclusion PET imaging is useful for assessing various types of anemia. It is also important to be aware of anemia-related PET findings to avoid mistaking them for malignancy or metastases.en_US
dc.identifier.doi10.1007/s40336-021-00442-z
dc.identifier.endpage509en_US
dc.identifier.issn2281-5872
dc.identifier.issn2281-7565
dc.identifier.issue5en_US
dc.identifier.scopus2-s2.0-85108873362en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage499en_US
dc.identifier.urihttps://doi.org/10.1007/s40336-021-00442-z
dc.identifier.urihttps://hdl.handle.net/20.500.14551/18444
dc.identifier.volume9en_US
dc.identifier.wosWOS:000668397100001en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherSpringer-Verlag Italia Srlen_US
dc.relation.ispartofClinical And Translational Imagingen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectAnemiaen_US
dc.subjectPETen_US
dc.subjectFDGen_US
dc.subjectFLTen_US
dc.subjectFe-52en_US
dc.subjectSickle-Cell-Diseaseen_US
dc.subjectPositron-Emission-Tomographyen_US
dc.subjectBone-Marrowen_US
dc.subjectAplastic-Anemiaen_US
dc.subjectIronen_US
dc.subjectCanceren_US
dc.subjectErythropoiesisen_US
dc.subjectDiagnosisen_US
dc.subjectPatienten_US
dc.subjectPharmacokineticsen_US
dc.titleAnemia and PET imagingen_US
dc.typeReview Articleen_US

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