Mean Platelet Volume in Patients With Dilated Cardiomyopathy: Does it have a Role in Left Ventricular Thrombus Formation?

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Tarih

2012

Dergi Başlığı

Dergi ISSN

Cilt Başlığı

Yayıncı

Sage Publications Inc

Erişim Hakkı

info:eu-repo/semantics/closedAccess

Özet

We assessed the clinical echocardiograhic, hematological, and biochemical parameters in patients with dilated cardiomyopathy (DCMP) and control individuals mainly focusing on the mean platelet volume (MPV) in terms of DCMP and left ventricle (LV) thrombus formation. Consecutive patients (n = 251) with DCMP and 266 patients without DCMP were studied. Mean platelet volume was significantly greater in patients with DCMP than in control patients (P < .05 for all comparisons). Comparing DCMP patients with LV thrombus (19 patients, 8%) and without LV thrombus (232 patients, 92%) showed that the prevalence of smokers was significantly higher and ejection fraction was significantly lower in patients with LV thrombus. We have shown that patients with DCMP have significantly higher MPV suggesting more platelet activation and the MPV of patients with DCMP and LV thrombus is comparable to those of patients without LV thrombus.

Açıklama

Anahtar Kelimeler

Mean Platelet Volume, Dilated Cardiomyopathy, Congestive Heart Failure, Platelet Activation, Left Ventricular Thrombus, Coronary-Artery-Disease, Two-Dimensional Echocardiography, Acute Myocardial-Infarction, Protein-C Resistance, Predictors, Risk, Inflammation, Survival, History

Kaynak

Angiology

WoS Q Değeri

Q3

Scopus Q Değeri

Q2

Cilt

63

Sayı

7

Künye