Dexmedetomidine: an alternative for epidural anesthesia in tension-free vaginal-tape surgery
Küçük Resim Yok
Tarih
2011
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Springer Tokyo
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
Anesthetic management of tension-free vaginal-tape (TVT) procedures is sometimes difficult to deal with, especially when surgeons request a cough test. Dexmedetomidine has unique sedative and analgesic properties while having minimal respiratory effects, making it suitable for perioperative use in monitored anesthesia care. We aimed to compare dexmedetomidine and epidural anesthesia in TVT patients. Forty-nine women [American Society of Anesthesiologists (ASA 1-3)] with genuine stress incontinence confirmed by preoperative bladder function studies were included in this double-blind, randomized study. The patients were randomly assigned to one of two groups: group D received 0.5 mu g/kg dexmedetomidine IV applied as bolus over 10 min and continued with 0.5 mu g/kg/h infusion, and local anesthesia (lidocaine 2% with epinephrine) performed by the surgeon. Group E received epidural anesthesia with 15 ml of 0.25% bupivacaine + 100 mu g fentanyl. Patients were monitored every 5 min for mean arterial pressure (MAP), heart rate (HR), peripheral oxygen saturation, respiratory rate, sedation, and intraoperative and postoperative pain. Ability to cough was also evaluated by the surgeon. There was no difference in ability to cough, and this was evaluated by the surgeon as adequate, and there was no difference in scores between groups. Significant decreases in MAP and HR were observed 10 min after the start of surgery in group D compared with group E, and they were significantly decreased until first and second postoperative hours, respectively (p < 0.05). None of the patients had respiratory rate decrease or apnea. Side effects encountered postoperatively were similar. Dexmedetomidine can be an alternative to epidural anesthesia in TVT procedure requiring cough test.
Açıklama
Anahtar Kelimeler
Dexmedetomidine, Epidural, Tension-Free Vaginal Tape, Female Urinary-Incontinence, Stress-Incontinence, Alpha-2-Adrenoceptor Agonist, Urethral Function, Tvt Procedure, Sedation, Management, Analgesia, Efficacy
Kaynak
Journal Of Anesthesia
WoS Q Değeri
Q4
Scopus Q Değeri
Q2
Cilt
25
Sayı
3
