The evaluation of Kaposi sarcoma patients diagnosed at a single center

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dc.authorwosidTurgut, Burhan/A-2517-2016
dc.contributor.authorPamuk, Guelsuem Emel
dc.contributor.authorDoenmez, Salim
dc.contributor.authorYesil, Yusuf
dc.contributor.authorTekguenduez, Emre
dc.contributor.authorTurgut, Burhan
dc.contributor.authorDemir, Muzaffer
dc.date.accessioned2024-06-12T11:13:54Z
dc.date.available2024-06-12T11:13:54Z
dc.date.issued2007
dc.departmentTrakya Üniversitesien_US
dc.description.abstractObjective: To determine the general clinical features, treatment modalities and response to treatment in 5 Kaposi sarcoma (KS) patients diagnosed at our center. Material and Methods: Five patients diagnosed with KS at Trakya University Medical Faculty, Department of Internal Medicine, Division of Hematology between October 2001-October 2006 were retrospectively evaluated. Results: KS developed secondary to immunosuppression in four of five patients, one had classical type KS. Four patients were males, and one was female. The diagnoses in patients who used immunosuppressive therapy were aplastic anemia, Hodgkin lymphoma, MDS-RAEB II, and chronic inflammatory demyelinating polyneuropathy (CIDP). We discontinued immunosuppressive therapy and administered vincristine in the aplastic anemia patient. KS lesions disappeared spontaneously although chemotherapy continued in the Hodgkin lymphoma case. KS lesions were present on initial presentation in the patient with MDS-RAEB H; there was prominent progression after chemotherapy and regression was achieved after paclitaxel. KS lesions disappeared spontaneously in the CIDP patient after discontinuation of corticosteroids. In the patient with classical type KS, KS lesions regressed after adriamycin and one persistent big lesion was surgically excised. Conclusion: There was partial or complete improvement of KS lesions after discontinuation of immunosuppressive drugs in some of our patients and with systemic chemotherapeutics in the others. As the diagnosis of this disease requires suspicion in especially early stages, hematologists should consider KS in the differential diagnosis of skin lesions in their immunosuppressive patients and a skin biopsy should be obtained.en_US
dc.identifier.endpage663en_US
dc.identifier.issn1300-0292
dc.identifier.issue5en_US
dc.identifier.scopus2-s2.0-37049032400en_US
dc.identifier.scopusqualityQ4en_US
dc.identifier.startpage658en_US
dc.identifier.urihttps://hdl.handle.net/20.500.14551/23718
dc.identifier.volume27en_US
dc.identifier.wosWOS:000254582800004en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isotren_US
dc.publisherOrtadogu Ad Pres & Publ Coen_US
dc.relation.ispartofTurkiye Klinikleri Tip Bilimleri Dergisien_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectSarcomaen_US
dc.subjectKaposien_US
dc.subjectImmunosuppressionen_US
dc.subjectHerpesvirus-Like Dnaen_US
dc.subjectTransplant Recipientsen_US
dc.subjectHuman-Herpesvirus-8en_US
dc.subjectSequencesen_US
dc.subjectTherapyen_US
dc.subjectUpdateen_US
dc.titleThe evaluation of Kaposi sarcoma patients diagnosed at a single centeren_US
dc.typeArticleen_US

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