Changing cerebral blood flow velocity detected by transcranial Doppler ultrasound during head up tilt in patients with multiple sclerosis

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dc.contributor.authorGonul, M.
dc.contributor.authorAsil, T.
dc.contributor.authorBalci, K.
dc.contributor.authorCelik, Y.
dc.contributor.authorTurgut, N.
dc.contributor.authorUzunca, I.
dc.date.accessioned2024-06-12T10:56:02Z
dc.date.available2024-06-12T10:56:02Z
dc.date.issued2008
dc.departmentTrakya Üniversitesien_US
dc.description.abstractBackground and purpose: Multiple sclerosis (MS) is a chronic inflammatory disease of central nervous system. We aimed to investigate the cerebral blood flow velocity (CBFV) changes in MS by transcranial Doppler. Methods: Twenty patients with MS, 20 age-matched healthy controls were included in the study. In both groups, blood flow velocities (BFVs) of middle cerebral arteries (MCAs) were evaluated. The changes of blood pressure, heart rate along with the changes in BFV of MCA were recorded after the patients were raised to upright position. Results: In both groups, upon raising the tilt table to the upright position, the mean CBFV values were found to be lower in comparison with the recorded baseline values (P values < 0.05). The decline in the mean CBFV values was more significant in patients with MS (P = 0.01). Conclusion: Our study showed upon raise of the tilt table, the mean BFVs decreased more in MS patients than control group with a more prominent change in the subgroup of MS patients with expanded disability scale scores >= 2. By use of transcranial Doppler ultrasound, it may be possible to evaluate BFV changes in patients with MS.en_US
dc.identifier.doi10.1111/j.1468-1331.2008.02179.x
dc.identifier.endpage729en_US
dc.identifier.issn1351-5101
dc.identifier.issue7en_US
dc.identifier.pmid18505409en_US
dc.identifier.scopus2-s2.0-44949247162en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage725en_US
dc.identifier.urihttps://doi.org/10.1111/j.1468-1331.2008.02179.x
dc.identifier.urihttps://hdl.handle.net/20.500.14551/19655
dc.identifier.volume15en_US
dc.identifier.wosWOS:000256634600016en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherWiley-Blackwellen_US
dc.relation.ispartofEuropean Journal Of Neurologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectCerebral Autoregulationen_US
dc.subjectHead Up Tilten_US
dc.subjectMultiple Sclerosisen_US
dc.subjectTranscranial Doppler Ultrasounden_US
dc.subjectCardiovascular Autonomic Dysfunctionen_US
dc.subjectDiabetic-Patientsen_US
dc.subjectAutoregulationen_US
dc.subjectDysautonomiaen_US
dc.subjectImpairmenten_US
dc.subjectSonographyen_US
dc.subjectLesionsen_US
dc.subjectMrien_US
dc.titleChanging cerebral blood flow velocity detected by transcranial Doppler ultrasound during head up tilt in patients with multiple sclerosisen_US
dc.typeArticleen_US

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