VALUE OF PULMONARY VASCULAR OBSTRUCTION INDEX FOR DETERMINING THROMBOLYTIC THERAPY

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dc.authoridBAYDIN, AHMET/0000-0003-4987-0878
dc.authoridSALT, OMER/0000-0002-5557-6627
dc.authoridGuzel, Murat/0000-0003-0276-4576
dc.authorwosidBAYDIN, AHMET/HLH-5259-2023
dc.authorwosidARSLAN AKSU, Esra/HII-2796-2022
dc.authorwosidErenler, Ali Kemal/AAA-2995-2020
dc.authorwosidBAYDIN, AHMET/AAG-4188-2019
dc.authorwosidGuzel, Murat/Q-3326-2016
dc.contributor.authorGuzel, Murat
dc.contributor.authorSoylu, Aysegul Idil
dc.contributor.authorSalt, Omer
dc.contributor.authorErenler, Ali Kemal
dc.contributor.authorTomak, Leman
dc.contributor.authorAksu, Esra Arslan
dc.contributor.authorAtay, Erdi
dc.date.accessioned2024-06-12T10:58:19Z
dc.date.available2024-06-12T10:58:19Z
dc.date.issued2016
dc.departmentTrakya Üniversitesien_US
dc.description.abstractIntroduction: An index for Pulmonaty Artery Computed Tomography Index Ratio (PACTOIR) may have important prognostic and therapeutic implications and as well as providing a standard to evaluate thrombolytic therapy response. The aim of this study was to determine whether PACTOIR predict the thrombolytic therapy in the treatment of pulmonary embolism (PE). Materials and methods: This retrospective study was conducted by reviewing charts of 52 patients (aged >= 18 years) who were admitted to our emergency department (ED) with initial diagnosis of pulmonary embolism and confirmed diagnosis of PE by Computed Tomography Pulmonary Angiography (CPTA). The patients were divided into two groups as follows: Group 1 (n=14) consisted of the patients who received thrombolytic therapy and Group 2 (n=38) consisted of the patients who did not receive thrombolytic therapy. PACTOIR was calculated in both groups to estimate thrombus load. We evaluated the effectiveness of thrombolytic therapy by comparing the levels of D-dieter and Troponin I. Results: Mean value for PACTOIR, D-dimer and Troponin I levels were 56.4 (%), 6.21 (mg/L) and 0.35 (mu g-IL) in Group 1 whereas they were 20.46 (%), 220 (mg/L) and 0.11 (mu g/L) in Group 2, respectively. Significant difference was detected between Group 1 and Group 2 (p<0.001). The sensitivity and specificity values were calculated as 92.9% and 89.5% for PACTOIR, whereas they were 85.7% and 78.9% for D-dimer, respectively. These values were found to be 78.6% and 65.8% for Troponin I, respectively. Conclusion: Based on our results, sensitivity to show PE severity and to determine thrombolytic therapy was significant when compared to D-dimer and Troponin I. In addition, we concluded that PACTOIR is the parameter with greatest sensitivity in determining the effectiveness of thrombolytic therapy.en_US
dc.identifier.doi10.19193/0393-6384_2016_3_95
dc.identifier.endpage815en_US
dc.identifier.issn0393-6384
dc.identifier.issn2283-9720
dc.identifier.issue3en_US
dc.identifier.scopus2-s2.0-84994234341en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage811en_US
dc.identifier.urihttps://doi.org/10.19193/0393-6384_2016_3_95
dc.identifier.urihttps://hdl.handle.net/20.500.14551/20011
dc.identifier.volume32en_US
dc.identifier.wosWOS:000376693400024en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherCarbone Editoreen_US
dc.relation.ispartofActa Medica Mediterraneaen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectComputed Tomography Pulmonary Angiographyen_US
dc.subjectPulmonary Artery Obstruction Indexen_US
dc.subjectPulmonary Embolismen_US
dc.subjectThrombolysisen_US
dc.subjectPrognostic Valueen_US
dc.subjectEmbolismen_US
dc.subjectCten_US
dc.subjectAngiographyen_US
dc.subjectSeverityen_US
dc.subjectQuantificationen_US
dc.subjectFibrinolysisen_US
dc.subjectMetaanalysisen_US
dc.titleVALUE OF PULMONARY VASCULAR OBSTRUCTION INDEX FOR DETERMINING THROMBOLYTIC THERAPYen_US
dc.typeArticleen_US

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