A low prevalance of purified protein derivative test positivity in Turkish patients with rheumatoid arthritis.: Association with clinical features and HRCT findings

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dc.authoridKarlikaya, Celal/0000-0001-7084-4987
dc.authorwosidCakir, Necati/AAG-7283-2019
dc.authorwosidKarlikaya, Celal/JMR-3834-2023
dc.contributor.authorKoker, I. H.
dc.contributor.authorPamuk, O. N.
dc.contributor.authorKarlikaya, C.
dc.contributor.authorTuncbilek, N.
dc.contributor.authorCakir, N.
dc.date.accessioned2024-06-12T11:13:40Z
dc.date.available2024-06-12T11:13:40Z
dc.date.issued2007
dc.departmentTrakya Üniversitesien_US
dc.description.abstractObjectives In this study, we aimed to evaluate the frequency of purified protein derivative (PPD) skin test positivity and associated clinical features in RA patients. Materials and methods We included 94 (80 F, 14 M, mean age: 55.8) consecutive RA patients with a disease duration of 8.7 years. PPD test was performed in all RA patients; clinical features were recorded down; chest x-ray, pulmonary function tests and HRCT were available in all cases. As the control group, we included data of 21 SLE, 44 AS, 27 OA, 16 gouty arthritis and 18 vasculitis patients. Results The frequencies of PPD positivity in RA (29.8%) and SLE (19%) patients were lower than in patients with AS (65.9%), gouty arthritis (68.8%) and OA (63%) (all p values < 0.01). PPD-positive RA patients were more frequently smokers (p = 0.005) and had a higher rate of RF seropositivity (p = 0.04) than PPD-negatives. PPD was less frequently positive in erosive RA disease (p = 0.033). Chest x-rays and HRCT abnormalities were detected in 41.8% and 62.7% of RA patients, respectively. Frequencies of chest x-ray and HRCT abnormalities in PPD-positive and PPD-negative patients were not difterent from each other (p > 0.05). Conclusion In our country in which tuberculosis is relatively frequent -contrary to the situation in AS patients- we observed a lower frequency of PPD positivity in RA and SLE patients compared to patients with other rheumatic diseases. We did not find any relationship between PPD positivity and the frequency of chest x-ray, HRCT abnormalities.en_US
dc.identifier.endpage59en_US
dc.identifier.issn0392-856X
dc.identifier.issn1593-098X
dc.identifier.issue1en_US
dc.identifier.pmid17417991en_US
dc.identifier.startpage54en_US
dc.identifier.urihttps://hdl.handle.net/20.500.14551/23645
dc.identifier.volume25en_US
dc.identifier.wosWOS:000245156600010en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherClinical & Exper Rheumatologyen_US
dc.relation.ispartofClinical And Experimental Rheumatologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectRheumatoid Arthritisen_US
dc.subjectTuberculosisen_US
dc.subjectHigh-Resolution Computerized Tomographyen_US
dc.subjectChest X-Rayen_US
dc.subjectPurified Protein Derivative (PPD) Testen_US
dc.subjectResolution Computed-Tomographyen_US
dc.subjectTuberculosisen_US
dc.subjectCriteriaen_US
dc.subjectClassificationen_US
dc.subjectPrevalenceen_US
dc.titleA low prevalance of purified protein derivative test positivity in Turkish patients with rheumatoid arthritis.: Association with clinical features and HRCT findingsen_US
dc.typeArticleen_US

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