Transferring the protective effect of remote ischemic preconditioning on skin flap among rats by blood serum

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dc.authoridOrhan, Abdullah Erkan/0000-0001-6532-5840
dc.authoridKaya, Oktay/0000-0001-9639-8022
dc.authoridGunduz, Ozgur/0000-0002-2470-3021
dc.authorid, ertan/0000-0002-3053-9133
dc.authoridoznur, meltem/0000-0002-6396-3168
dc.authorwosidŞahin, Ertan/AAG-8999-2020
dc.authorwosidGÜNDÜZ, Özgür/AAH-8717-2019
dc.authorwosidOrhan, Abdullah Erkan/A-6237-2017
dc.authorwosidKaya, Oktay/JGL-9169-2023
dc.authorwosidGunduz, Ozgur/A-2351-2016
dc.contributor.authorOrhan, Erkan
dc.contributor.authorGunduz, Ozgur
dc.contributor.authorKaya, Oktay
dc.contributor.authorOznur, Meltem
dc.contributor.authorSahin, Ertan
dc.date.accessioned2024-06-12T11:13:30Z
dc.date.available2024-06-12T11:13:30Z
dc.date.issued2019
dc.departmentTrakya Üniversitesien_US
dc.description.abstractThe aim of this study was to show whether the protective effect of remote ischemic preconditioning (RIPC) on flaps can be transferred among different individuals with the transfusion of blood serum. Blood serum was taken from rats without any procedure (Group x), rats 1 hour (Group y) and 24 hours (Group z) after performing RIPC and the remaining rats were divided into six groups. While the random pattern skin flap was performed only in the back region in Group 1, and it was performed 1 hour (Group 2) and 24 hours (Group 3) after induction RIPC. Flap surgery was performed after the intravenous injection of serum obtained from Group x in Group 4, from Group y in Group 5, and from Group z in Group 6. After 7 days, the ratios of viable areas in the flaps of the remaining rats were calculated. When the viable area ratios in the flaps to the whole flap area were calculated, it was found out that the viable area ratios in Group 2 (61.6%), Group 3 (75.6%) and Group 6 (74.2%) were statistically significantly higher compared to Group 1 (51.5%), Group 4 (52.6%) and Group 5 (58.7%), that viable area ratios in Groups 3 and 6 were statistically significantly higher compared to Group 2, and that there was no difference between Groups 3 and 6. This study showed that RIPC forms a protective effect on the flaps and that this effect could be transferred among individuals with blood serum.en_US
dc.identifier.doi10.1080/2000656X.2019.1582422
dc.identifier.endpage203en_US
dc.identifier.issn2000-656X
dc.identifier.issn2000-6764
dc.identifier.issue4en_US
dc.identifier.pmid30888241en_US
dc.identifier.scopus2-s2.0-85063076699en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage198en_US
dc.identifier.urihttps://doi.org/10.1080/2000656X.2019.1582422
dc.identifier.urihttps://hdl.handle.net/20.500.14551/23581
dc.identifier.volume53en_US
dc.identifier.wosWOS:000480623800002en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherTaylor & Francis Ltden_US
dc.relation.ispartofJournal Of Plastic Surgery And Hand Surgeryen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectRemote Ischemic Preconditionen_US
dc.subjectFlapen_US
dc.subjectBlood Serumen_US
dc.subjectReperfusion Injuryen_US
dc.subjectMyocardial Protectionen_US
dc.subjectMuscleen_US
dc.titleTransferring the protective effect of remote ischemic preconditioning on skin flap among rats by blood serumen_US
dc.typeArticleen_US

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